Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 14/20 | 0.55 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.44 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.44 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7771514 | 0.89 | ACHE (0.62) | ACHEEPHX2 | |
| SCHEMBL7769261 | 0.84 | ACHE (0.44) | ACHE | |
| SCHEMBL5700191 | 0.81 | ACHE (0.65) | ACHECHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL7769333 | 0.81 | ACHE (0.55) | ACHECHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL29380101 | 0.80 | ACHE (0.59) | ACHECHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL7773553 | 0.80 | ACHE (0.48) | ACHECHRNB2CHRNB4CHRNA3CHRNA4 | |
| Ammonia Solution, Strong SCHEMBL28282442 | 0.79 | ACHE (0.63) | ACHECHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL7564851 | 0.79 | ACHE (0.76) | ACHEEPHX2 | |
| Hydrochloric Acid SCHEMBL27825731 | 0.79 | ACHE (0.63) | ACHECHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL7773651 | 0.78 | ACHE (0.44) | ACHEEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0765879-B1 | 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests | SANKYO CO (JP) | 2001-02-14 | — | — | EP | disclosed |
| US-5861429-A | MITICIDES AND ANTHELMINTICS | SANKYO COMPANY, LIMITED (JP) | 1999-01-19 | — | — | US | disclosed |
| EP-0765879-A1 | 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests | SANKYO COMPANY LIMITED (JP) | 1997-04-02 | — | — | EP | disclosed |