Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 1.00 |
| ▸ | TSHR | P16473 | 1/20 | 1.00 |
| ▸ | HTT | P42858 | 1/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9748549 | 0.89 | ALDH1A1 (0.80) | ALDH1A1TSHRHTTKMT2ASMN1; SMN2 | |
| SCHEMBL5683703 | 0.88 | ALDH1A1 (0.77) | ALDH1A1TSHRHTTKMT2ASMN1; SMN2 | |
| SCHEMBL9577558 | 0.85 | ALDH1A1 (0.73) | ALDH1A1TSHRHTTKMT2ASMN1; SMN2 | |
| SCHEMBL17386414 | 0.83 | ALDH1A1 (0.71) | ALDH1A1TSHRHTTKMT2AMEN1 | |
| SCHEMBL6406725 | 0.82 | ALDH1A1 (0.69) | ALDH1A1TSHRHTTKMT2ASMN1; SMN2 | |
| SCHEMBL4797170 | 0.82 | ALDH1A1 (0.69) | ALDH1A1TSHRHTTKMT2ASMN1; SMN2 | |
| SCHEMBL9577396 | 0.80 | ALDH1A1 (0.67) | ALDH1A1TSHRHTTKMT2ASMN1; SMN2 | |
| SCHEMBL3999764 | 0.80 | ALDH1A1 (0.67) | ALDH1A1TSHRHTTKMT2ASMN1; SMN2 | |
| SCHEMBL7385780 | 0.80 | ALDH1A1 (0.67) | ALDH1A1TSHRHTTKMT2ASMN1; SMN2 | |
| SCHEMBL5325708 | 0.80 | ALDH1A1 (0.67) | ALDH1A1TSHRHTTKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0765879-B1 | 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests | SANKYO CO (JP) | 2001-02-14 | — | — | EP | disclosed |
| US-5861429-A | MITICIDES AND ANTHELMINTICS | SANKYO COMPANY, LIMITED (JP) | 1999-01-19 | — | — | US | disclosed |
| EP-0765879-A1 | 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests | SANKYO COMPANY LIMITED (JP) | 1997-04-02 | — | — | EP | disclosed |