Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.65 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.63 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.55 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.55 |
| ▸ | ICMT | O60725 | 1/20 | 0.54 |
| ▸ | ALB | P02768 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.51 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.51 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7566432 | 1.00 | EPHX1 (0.65) | EPHX1EPHX2HDAC3HDAC1HDAC2 | |
| SCHEMBL7568943 | 0.96 | EPHX2 (0.64) | EPHX1EPHX2HDAC3HDAC1HDAC2 | |
| SCHEMBL7764576 | 0.92 | EPHX1 (0.64) | EPHX1EPHX2HDAC3HDAC1HDAC2 | |
| SCHEMBL7568901 | 0.92 | EPHX1 (0.64) | EPHX1EPHX2HDAC3HDAC1HDAC2 | |
| SCHEMBL7764577 | 0.83 | BCHE (0.56) | EPHX1EPHX2HDAC3HDAC1HDAC2 | |
| SCHEMBL12196026 | 0.79 | EPHX1 (1.00) | EPHX1EPHX2HDAC1HDAC2SMN1; SMN2 | |
| SCHEMBL8022082 | 0.78 | EPHX1 (0.48) | EPHX1EPHX2HDAC3HDAC1HDAC2 | |
| SCHEMBL8565479 | 0.78 | EPHX1 (0.48) | EPHX1EPHX2HDAC3HDAC1HDAC2 | |
| SCHEMBL22301532 | 0.78 | EPHX1 (0.97) | EPHX1EPHX2HDAC3HDAC1HDAC2 | |
| SCHEMBL12932000 | 0.78 | EPHX2 (1.00) | EPHX1EPHX2HDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0929515-B1 | NOVEL PHENOXYETHYLAMINE DERIVATIVES, METHOD OF PREPARATION, APPLICATION AS MEDICINE AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | CONSEILS DE RECH S SOC D (FR) | 2001-06-20 | — | — | EP | disclosed |
| US-6150417-A | ADMINISTERING TO WARM BLOODED ANIMALS COMPOUNDS SUCH AS N-TERT-BUTYL-5-((2-(2-METHOXYPHENOXY)ETHYL)AMINO)PENTANAMIDE FOR INDUCING ANTIEMETIC ACTIVITY; TREATING ANXIETY, DEPRESSION, AND SLEEP DISORDERS | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (FR) | 2000-11-21 | — | — | US | disclosed |
| US-5998666-A | ANTIULCER, ANTISECRETORY AGENTS; ANTIEMITIC | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (FR) | 1999-12-07 | — | — | US | disclosed |
| EP-0929515-A1 | NOVEL PHENOXYETHYLAMINE DERIVATIVES, METHOD OF PREPARATION, APPLICATION AS MEDICINE AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 1999-07-21 | — | — | EP | disclosed |
| WO-1998013337-A1 | NOVEL PHENOXYETHYLAMINE DERIVATIVES, METHOD OF PREPARATION, APPLICATION AS MEDICINE AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 1998-04-02 | — | — | WO | disclosed |