Sorbitol

Sorbitol

SCHEMBL7769394

C=CC(=C)C.OCCO.OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)CO

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
TDP1 Q9NUW8 1/20 0.48
ALDH1A1 P00352 1/20 0.46
TP53 P04637 1/20 0.46
TSHR P16473 1/20 0.46
KDM4E B2RXH2 2/20 0.41
PDE4A P27815 1/20 0.37
USP2 O75604 1/20 0.34
SLCO1B1 Q9Y6L6 1/20 0.34
TOP1 P11387 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sorbitol SCHEMBL2418929 0.83 LMNA (0.58) LMNAL3MBTL1TDP1KDM4EPDE4A
Mannitol SCHEMBL22575783 0.83 LMNA (0.58) LMNAL3MBTL1TDP1KDM4EPDE4A
Demannose SCHEMBL13518380 0.82 LMNA (0.41) LMNAL3MBTL1TDP1ALDH1A1TP53
Ethylene Glycol SCHEMBL35862 0.80
Mannitol SCHEMBL28092438 0.78 LMNA (0.65) LMNAL3MBTL1TDP1ALDH1A1TSHR
Sorbitol SCHEMBL11254388 0.77 LMNA (0.85) LMNAL3MBTL1TDP1ALDH1A1TSHR
Sorbitol SCHEMBL4165943 0.77 LMNA (0.85) LMNAL3MBTL1TDP1ALDH1A1TSHR
Mannitol SCHEMBL21066268 0.77 LMNA (0.85) LMNAL3MBTL1TDP1ALDH1A1TSHR
Mannitol SCHEMBL21081888 0.77 LMNA (0.85) LMNAL3MBTL1TDP1ALDH1A1TSHR
Mannitol SCHEMBL4293781 0.77 LMNA (0.85) LMNAL3MBTL1TDP1ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1113784-A1 USE OF ISOPARAFFIN EXTENDERS FOR CLEAR GEL COSMETIC COMPOSITIONS ExxonMobil Chemical Patents Inc. (US) 2001-07-11 EP disclosed
WO-2000015191-A1 USE OF ISOPARAFFIN EXTENDERS FOR CLEAR GEL COSMETIC COMPOSITIONS EXXON CHEMICAL PATENTS INC. (US) 2000-03-23 WO disclosed