Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 13/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.37 |
| ▸ | MEN1 | O00255 | 5/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | TYR | P14679 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11211118 | 0.87 | TYR (0.47) | KDM4EALDH1A1MAPK1LMNAMAPT | |
| SCHEMBL11211380 | 0.84 | TYR (0.50) | KDM4EALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL11214719 | 0.84 | KDM4E (0.48) | KDM4EALDH1A1MAPK1LMNAMAPT | |
| SCHEMBL11131096 | 0.82 | TYR (0.44) | KDM4EALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL11216542 | 0.82 | TYR (0.44) | KDM4EALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL11208013 | 0.82 | TYR (0.44) | KDM4EALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL8821197 | 0.78 | ALDH1A1 (0.47) | KDM4EALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL621548 | 0.78 | KDM4E (0.39) | KDM4EALDH1A1MAPK1LMNAMAPT | |
| SCHEMBL11212583 | 0.77 | KDM4E (0.45) | KDM4EALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL7773778 | 0.75 | KDM4E (0.38) | KDM4EALDH1A1MAPK1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0776948-B1 | Mixtures of pyridone monoazo dyestuffs | CIBA SC HOLDING AG (CH) | 2001-08-01 | — | — | EP | disclosed |
| EP-0776948-A1 | Mixtures of pyridone monoazo dyestuffs | Ciba SC Holding AG (CH) | 1997-06-04 | — | — | EP | disclosed |
| EP-0297397-B1 | PREPARATION OF DIAZO AND AZO COMPOUNDS | BAYER AG (DE) | 1993-08-04 | — | — | EP | disclosed |
| US-4942225-A | Preparation of diazo and azo compounds using azidoformamidium salts | BAYER AKTIENGESELLSCHAFT (DE) | 1990-07-17 | — | — | US | disclosed |
| EP-0297397-A2 | Preparation of diazo and azo compounds | BAYER AG (DE) | 1989-01-04 | — | — | EP | disclosed |