SCHEMBL776947

SCHEMBL776947

O=S(O)(O)(c1ccccc1)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.33

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CES1 P23141 2/20 0.33
ELANE P08246 1/20 0.33
PTPN1 P18031 1/20 0.32
NR1H2 P55055 3/20 0.32
NR1H3 Q13133 2/20 0.31
PDK1 Q15118 2/20 0.30
PDK2 Q15119 2/20 0.30
PDK3 Q15120 2/20 0.30
PDK4 Q16654 2/20 0.30
ALDH1A1 P00352 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL775619 0.94 CES1 (0.32) CES1ELANEPTPN1
SCHEMBL776323 0.88 CES1 (0.35) CES1PTPN1PDK1PDK2PDK3
SCHEMBL778297 0.79 CES1 (0.35) CES1PTPN1PDK1PDK2PDK3
SCHEMBL775656 0.79 CES1 (0.38) CES1PTPN1ALDH1A1TSHR
SCHEMBL775658 0.67 CES1 (0.33) CES1PTPN1
SCHEMBL5042529 0.66 CES1 (0.33) CES1PTPN1ALDH1A1TSHR
SCHEMBL778850 0.65 CES1 (0.34) CES1PTPN1ALDH1A1TSHR
SCHEMBL776409 0.65 CES1 (0.35) CES1PTPN1ALDH1A1TSHR
SCHEMBL278265 0.65 TSHR (0.39) CES1ALDH1A1TSHR
SCHEMBL776915 0.65 THRB (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9343777-B2 Non-aqueous liquid electrolyte and non-aqueous liquid electrolyte secondary battery MITSUBISHI CHEMICAL CORPORATION (JP) 2016-05-17 US disclosed
US-9252457-B2 Non-aqueous liquid electrolyte and non-aqueous liquid electrolyte secondary battery MITSUBISHI CHEMICAL CORPORATION (JP) 2016-02-02 US disclosed
US-20120177988-A1 NON-AQUEOUS LIQUID ELECTROLYTE AND NON-AQUEOUS LIQUID ELECTROLYTE SECONDARY BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2012-07-12 US disclosed
US-20120070731-A1 NON-AQUEOUS LIQUID ELECTROLYTE AND NON-AQUEOUS LIQUID ELECTROLYTE SECONDARY BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2012-03-22 US disclosed
US-20090325065-A1 NON-AQUEOUS LIQUID ELECTROLYTE AND NON-AQUEOUS LIQUID ELECTROLYTE SECONDARY BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2009-12-31 US disclosed