Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 17/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 12/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 9/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6328526 | 0.89 | ADRB3 (0.46) | ADRB3ADRB2ADRB1CYP19A1 | |
| SCHEMBL7768576 | 0.86 | ADRB3 (0.57) | ADRB3ADRB2ADRB1 | |
| SCHEMBL6322905 | 0.84 | ADRB3 (0.61) | ADRB3ADRB2ADRB1 | |
| SCHEMBL6322913 | 0.84 | ADRB3 (0.61) | ADRB3ADRB2ADRB1 | |
| SCHEMBL7769483 | 0.84 | ADRB3 (0.45) | ADRB3ADRB2ADRB1CYP19A1 | |
| SCHEMBL6322651 | 0.79 | ADRB3 (0.58) | ADRB3 | |
| SCHEMBL6321884 | 0.79 | ADRB3 (0.58) | ADRB3 | |
| SCHEMBL7079186 | 0.78 | KEAP1 (0.43) | ADRB3ADRB2ADRB1CYP19A1 | |
| SCHEMBL4816663 | 0.78 | CYP19A1 (0.48) | ADRB3ADRB2ADRB1CYP19A1 | |
| SCHEMBL6328531 | 0.77 | TRPV1 (0.42) | ADRB3ADRB2ADRB1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1107944-A1 | AMINOALCOHOL DERIVATIVES AND THEIR USE AS BETA 3 ADRENERGIC AGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-06-20 | — | — | EP | disclosed |
| WO-2000012462-A1 | AMINOALCOHOL DERIVATIVES AND THEIR USE AS BETA 3 ADRENERGIC AGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-03-09 | — | — | WO | disclosed |