Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CETP | P11597 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26492558 | 0.88 | EPHX1 (0.41) | LMNACNR1SPHK1PLA2G10EPHX1 | |
| SCHEMBL16390557 | 0.86 | LMNA (0.50) | LMNAKDM4ECNR1ADRA1ATDP1 | |
| SCHEMBL2042310 | 0.85 | LMNA (0.48) | LMNAKDM4ECNR1ADRA1ATDP1 | |
| SCHEMBL16389830 | 0.85 | LMNA (0.48) | LMNAKDM4ECNR1ADRA1ATDP1 | |
| SCHEMBL1290325 | 0.85 | LMNA (0.48) | LMNAKDM4ECNR1ADRA1ATDP1 | |
| SCHEMBL544925 | 0.85 | LMNA (0.48) | LMNAKDM4ECNR1ADRA1ATDP1 | |
| SCHEMBL16390516 | 0.85 | LMNA (0.48) | LMNAKDM4ECNR1ADRA1ATDP1 | |
| SCHEMBL3826478 | 0.85 | LMNA (0.48) | LMNAKDM4ECNR1ADRA1ATDP1 | |
| SCHEMBL2037547 | 0.85 | LMNA (0.48) | LMNAKDM4ECNR1ADRA1ATDP1 | |
| SCHEMBL5865607 | 0.85 | LMNA (0.48) | LMNAKDM4ECNR1ADRA1ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0721446-B1 | CHIRAL SURFACTANTS AND METHODS FOR THEIR USE IN CHIRAL SEPARATIONS | WATERS CORP (US) | 2001-07-18 | — | — | EP | disclosed |