SCHEMBL7769664

SCHEMBL7769664

CCC(=O)[N]NC(=O)CF

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7828826 0.83 KMT2A (0.39) MEN1KMT2A
SCHEMBL7769331 0.83 HDAC3 (0.38)
SCHEMBL7771427 0.79 CES1 (0.38) MEN1KMT2A
SCHEMBL7770619 0.79 KDM4E (0.38) MEN1KMT2A
SCHEMBL7765939 0.78 ALDH1A1 (0.41) MEN1KMT2A
SCHEMBL7765728 0.77 SMN1; SMN2 (0.36) MEN1KMT2A
SCHEMBL7765959 0.77 MEN1 (0.30) MEN1KMT2A
SCHEMBL7765931 0.76
SCHEMBL5147124 0.73
SCHEMBL7773730 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0765879-B1 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests SANKYO CO (JP) 2001-02-14 EP disclosed
US-5861429-A MITICIDES AND ANTHELMINTICS SANKYO COMPANY, LIMITED (JP) 1999-01-19 US disclosed
EP-0765879-A1 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests SANKYO COMPANY LIMITED (JP) 1997-04-02 EP disclosed