SCHEMBL7769815

SCHEMBL7769815

CCCCCCCCCOC(=O)c1ccc(OC(=O)c2ccccc2O)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.61
ALDH1A1 P00352 4/20 0.61
MEN1 O00255 1/20 0.61
HPGD P15428 1/20 0.61
KMT2A Q03164 1/20 0.61
TSHR P16473 4/20 0.59
LMNA P02545 2/20 0.59
STS P08842 6/20 0.58
MAPK1 P28482 2/20 0.57
TP53 P04637 1/20 0.57
CYP3A4 P08684 1/20 0.57
ESR1 P03372 1/20 0.56
CYP1A2 P05177 1/20 0.56
CYP2D6 P10635 1/20 0.56
CYP2C19 P33261 1/20 0.56
NR1H2 P55055 1/20 0.56
RNASEL Q05823 1/20 0.56
SMN1; SMN2 Q16637 1/20 0.56
NPC1 O15118 1/20 0.56
RAB9A P51151 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7777054 1.00 MAPT (0.61) MAPTALDH1A1MEN1HPGDKMT2A
SCHEMBL7774424 1.00 MAPT (0.61) MAPTALDH1A1MEN1HPGDKMT2A
SCHEMBL6565192 0.96 TSHR (0.60) MAPTALDH1A1MEN1HPGDKMT2A
SCHEMBL7621530 0.90 KMT2A (0.60) MAPTALDH1A1MEN1HPGDKMT2A
SCHEMBL10944031 0.87 HPGD (0.58) MAPTALDH1A1HPGDTSHRLMNA
SCHEMBL4731100 0.85 ALDH1A1 (0.81) ALDH1A1TSHRLMNAMAPK1TP53
SCHEMBL19373812 0.85 MAPT (0.74) MAPTALDH1A1MEN1HPGDKMT2A
SCHEMBL8927962 0.85 ALDH1A1 (0.81) ALDH1A1TSHRLMNAMAPK1TP53
SCHEMBL19373815 0.85 MAPT (0.74) MAPTALDH1A1MEN1HPGDKMT2A
SCHEMBL2801630 0.85 ALDH1A1 (0.81) ALDH1A1TSHRLMNAMAPK1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140004071-A1 Thermochromic Dental Material BROWN WILLIAM STEVEN (US) 2014-01-02 US disclosed
EP-0748698-B1 Thermal recording sheet JUJO PAPER CO LTD (JP) 2001-08-22 EP disclosed
US-6184300-B1 USEFUL AS HEAT-INSULATING MATERIAL, ORGANIC PIGMENT, OR OPACIFYING AGENT, AND AS HEAT-INSULATING INTERLAYER TO BE FORMED IN THERMAL RECORDING MATERIAL NIPPON ZEON CO., LTD. (JP) 2001-02-06 US disclosed
EP-0699662-B1 Novel urea (thiourea) derivative and thermal recording sheet using same JUJO PAPER CO LTD (JP) 1998-10-21 EP disclosed
US-5747414-A SUBSTRATE WITH COLOR LAYER, ALUMINUM HYDROXIDE AND A RESIN OF UREA-FORMALDEHYDE AND DEVELOPERS NIPPON PAPER INDUSTRIES, LTD. (JP) 1998-05-05 US disclosed
US-5665675-A THERMAL RECORDING MEDIUM NIPPON PAPER INDUSTRIES CO., LTD. (JP) 1997-09-09 US disclosed
US-5661100-A HAVING HIGH SENSITIVITY, SUPERIOR THERMAL RESISTANCE, WATER RESISTANCE, OIL RESISTANCE NIPPON PAPER INDUSTRIES CO., LTD. (JP) 1997-08-26 US disclosed
EP-0693386-B1 Aminobenzenesulfonamide derivatives as colour-developers for thermosensitive recording materials JUJO PAPER CO LTD (JP) 1997-02-05 EP disclosed
EP-0559386-B1 Thermal recording sheet JUJO PAPER CO LTD (JP) 1997-01-15 EP disclosed
EP-0748698-A2 Thermal recording sheet NIPPON PAPER INDUSTRIES CO., LTD. (JP) 1996-12-18 EP disclosed
US-5322831-A Color developers, chromogenic dye, stabilizer and sensitizer JUJO PAPER CO., LTD. (JP) 1994-06-21 US disclosed
EP-0559386-A2 Thermal recording sheet NIPPON PAPER INDUSTRIES CO., LTD. (JP) 1993-09-08 EP disclosed
EP-0391434-B1 THERMOSENSITIVE RECORDING SHEET JUJO PAPER CO., LTD. (JP) 1993-06-30 EP disclosed
EP-0289041-B1 THERMOSENSITIVE RECORDING SHEET JUJO PAPER CO., LTD. (JP) 1993-03-24 EP disclosed
US-5096873-A Containign a support, color developer layer with a basic leuco dye in it; high density speed recording, image storage stability JUJO PAPER CO., LTD. (JP) 1992-03-17 US disclosed
US-4971942-A Colorless basic chromogenic cye, divinyl compound, fluorane-type leuco dye JUJO PAPER CO., LTD. (JP) 1990-11-20 US disclosed
EP-0391434-A1 Thermosensitive recording sheet JUJO PAPER CO., LTD. (JP) 1990-10-10 EP disclosed
US-4918044-A LEUCO DYE, COLOR DEVELOPER, BIPHENYL TOLYL ETHER SENSITIZER, STABLE, HIGH DENSITY, HIGH SPEED RECORDING JUJO PAPER CO., LTD. (JP) 1990-04-17 US disclosed
US-4853362-A Heat-sensitive recording sheet JUJO PAPER CO., LTD. (JP) 1989-08-01 US disclosed
EP-0289041-A2 Thermosensitive recording sheet JUJO PAPER CO., LTD. (JP) 1988-11-02 EP disclosed