Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 11/20 | 0.75 |
| ▸ | DRD3 | P35462 | 10/20 | 0.75 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.74 |
| ▸ | DRD4 | P21917 | 4/20 | 0.67 |
| ▸ | HTR2A | P28223 | 9/20 | 0.60 |
| ▸ | HTR2C | P28335 | 9/20 | 0.60 |
| ▸ | HTR1A | P08908 | 3/20 | 0.60 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7766264 | 0.99 | DRD2 (0.73) | DRD2DRD3ADRA1ADRD4HTR2A | |
| Hydrochloric Acid SCHEMBL7535217 | 0.92 | DRD2 (0.73) | DRD2DRD3ADRA1ADRD4HTR2A | |
| Hydrochloric Acid SCHEMBL7421291 | 0.89 | DRD3 (0.81) | DRD2DRD3ADRA1ADRD4HTR2A | |
| Hydrochloric Acid SCHEMBL7421290 | 0.89 | DRD3 (0.81) | DRD2DRD3ADRA1ADRD4HTR2A | |
| SCHEMBL7769974 | 0.87 | DRD2 (0.76) | DRD2DRD3ADRA1ADRD4HTR2A | |
| SCHEMBL7766329 | 0.87 | DRD3 (0.89) | DRD2DRD3ADRA1ADRD4HTR2A | |
| Hydrochloric Acid SCHEMBL7766165 | 0.86 | DRD2 (0.75) | DRD2DRD3ADRA1ADRD4HTR2A | |
| SCHEMBL7765356 | 0.86 | DRD2 (0.76) | DRD2DRD3ADRA1ADRD4HTR2A | |
| Hydrochloric Acid SCHEMBL7762622 | 0.86 | DRD3 (0.88) | DRD2DRD3ADRA1ADRD4HTR2A | |
| Hydrochloric Acid SCHEMBL7765433 | 0.85 | DRD2 (0.75) | DRD2DRD3ADRA1ADRD4HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0873329-B1 | NOVEL N-AMINOALKYLFLUORENECARBOXAMIDES; A NEW CLASS OF DOPAMINE RECEPTOR SUBTYPE SPECIFIC LIGANDS | NEUROGEN CORP (US) | 2001-06-06 | — | — | EP | claimed |