⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL238159 | 0.67 | — | — | |
| SCHEMBL7328700 | 0.63 | — | — | |
| SCHEMBL1533675 | 0.61 | — | — | |
| Bicarbonate SCHEMBL29253173 | 0.57 | TRIM24 (0.41) | — | |
| Bicarbonate SCHEMBL1935351 | 0.54 | — | — | |
| Bicarbonate SCHEMBL3735671 | 0.54 | — | — | |
| Bicarbonate SCHEMBL1829439 | 0.50 | CA4 (0.46) | — | |
| Bicarbonate SCHEMBL31070829 | 0.50 | — | — | |
| Bicarbonate SCHEMBL5967928 | 0.50 | CA4 (0.46) | — | |
| Bicarbonate SCHEMBL9678485 | 0.50 | CA4 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170334948-A1 | LIGANDS FOR ANTIBODY AND FC-FUSION PROTEIN PURIFICATION BY AFFINITY CHROMOTOGRAPHY IV | NOVALIX DEUTSCHLAND GMBH (DE) | 2017-11-23 | — | — | US | disclosed |
| US-9745339-B2 | Ligands for antibody and Fc-fusion protein purification by affinity chromotography IV | NOVALIX DEUTSCHLAND GMBH (DE) | 2017-08-29 | — | — | US | disclosed |
| US-20160009760-A1 | LIGANDS FOR ANTIBODY AND FC-FUSION PROTEIN PURIFICATION BY AFFINITY CHROMOTOGRAPHY IV | GRAFFINITY PHARMACEUTICALS GMBH (DE) | 2016-01-14 | — | — | US | disclosed |
| EP-2812346-A1 | LIGANDS FOR ANTIBODY AND FC-FUSION PROTEIN PURIFICATION BY AFFINITY CHROMOTOGRAPHY IV | Graffinity Pharmaceuticals GmbH (DE) | 2014-12-17 | — | — | EP | disclosed |
| WO-2014020152-A1 | LIGANDS FOR APHERESIS AND IMMUNOABSORPTION | GRAFFINITY PHARMACEUTICALS GMBH (DE) | 2014-02-06 | — | — | WO | disclosed |
| WO-2013117707-A1 | LIGANDS FOR ANTIBODY AND FC-FUSION PROTEIN PURIFICATION BY AFFINITY CHROMOTOGRAPHY IV | GRAFFINITY PHARMACEUTICALS GMBH (DE) | 2013-08-15 | — | — | WO | disclosed |
| EP-1108214-A1 | METHOD FOR SCREENING LIGAND AFFINITY AND TOOL FOR USE IN THE METHOD | Amersham Pharmacia Biotech AB (SE) | 2001-06-20 | — | — | EP | disclosed |
| WO-2000014541-A1 | METHOD FOR SCREENING LIGAND AFFINITY AND TOOL FOR USE IN THE METHOD | AMERSHAM PHARMACIA BIOTECH AB (SE) | 2000-03-16 | — | — | WO | disclosed |
| CN-1126441-A | Amplification of vitamin B12 absorption System Using polymers | BIOTECH AUSTRALIA PTY LTD (AU) | 1996-07-10 | — | — | CN | disclosed |