SCHEMBL7770503

SCHEMBL7770503

C[Si](C)=[Zr](c1ccccc1)(c1ccccc1)(c1cccc2c1Cc1ccccc1-2)c1cccc2c1Cc1ccccc1-2

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PNMT P11086 1/20 0.41
NPC1 O15118 2/20 0.39
RAB9A P51151 2/20 0.39
HTR7 P34969 1/20 0.34
HTR2B P41595 1/20 0.34
PGR P06401 1/20 0.33
KDR P35968 1/20 0.31
ADORA2A P29274 1/20 0.31
ADORA1 P30542 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA4 P22748 1/20 0.31
CA6 P23280 1/20 0.31
DRD2 P14416 1/20 0.31
DRD4 P21917 1/20 0.31
DRD3 P35462 1/20 0.31
MAOA P21397 1/20 0.31
BCHE P06276 1/20 0.31
ACHE P22303 1/20 0.31
SRD5A2 P31213 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7766800 0.80 PNMT (0.44) PNMTNPC1RAB9AHTR7HTR2B
SCHEMBL3119422 0.78 PNMT (0.42) PNMTNPC1RAB9AHTR7HTR2B
SCHEMBL7930905 0.77 PNMT (0.45) PNMTNPC1RAB9AHTR7HTR2B
SCHEMBL6557454 0.76 PNMT (0.44) PNMTNPC1RAB9AHTR7HTR2B
SCHEMBL9217933 0.76 PNMT (0.41) PNMTNPC1RAB9AHTR7HTR2B
Hydrochloric Acid SCHEMBL6558701 0.75 PNMT (0.42) PNMTNPC1RAB9AHTR7HTR2B
Hydrochloric Acid SCHEMBL3126691 0.75 PNMT (0.42) PNMTNPC1RAB9AHTR7HTR2B
SCHEMBL6557465 0.74 PNMT (0.47) PNMTNPC1RAB9AHTR7HTR2B
SCHEMBL9223366 0.72 PNMT (0.46) PNMTNPC1RAB9AHTR7HTR2B
SCHEMBL7716985 0.72 PNMT (0.46) PNMTNPC1RAB9AHTR7HTR2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0678530-B1 Process for production of cyclic olefin copolymers and copolymers produced by said process MITSUI CHEMICALS INC (JP) 2001-07-25 EP disclosed
EP-0719803-B1 Process for the production of cycloolefin random copolymer MITSUI CHEMICALS INC (JP) 2001-03-21 EP disclosed
US-5650471-A COPOLYMERIZING AN ALPHA-OLEFIN AND A CYCLOOLEFIN IN THE PRESENCE OF A CATALYST FORMED FROM A TRANSITION METAL COMPOUND AND AN ORGANIC ALUMINUM COMPOUND MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1997-07-22 US disclosed
US-5559199-A MOLECULAR WEIGHT CONTROL MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1996-09-24 US disclosed
EP-0729983-A2 Process for the production of cycloolefin random copolymer MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1996-09-04 EP disclosed
EP-0719803-A2 Process for the production of cycloolefin random copolymer MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1996-07-03 EP disclosed
EP-0678530-A1 Process for production of cyclic olefin copolymers and copolymers produced by said process MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1995-10-25 EP disclosed