Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1157607 | 0.85 | ALDH1A1 (0.35) | ALDH1A1TDP1CYP2D6TSHRCYP2C19 | |
| SCHEMBL1681817 | 0.82 | ALDH1A1 (0.33) | ALDH1A1TDP1CYP2D6TSHRCYP2C19 | |
| SCHEMBL28900863 | 0.82 | ALDH1A1 (0.33) | ALDH1A1TDP1CYP2D6TSHRCYP2C19 | |
| Acetic Acid SCHEMBL8992542 | 0.82 | FFAR3 (0.39) | ALDH1A1TDP1CYP2D6TSHRCYP2C19 | |
| SCHEMBL610850 | 0.82 | ALDH1A1 (0.33) | ALDH1A1TDP1CYP2D6TSHRCYP2C19 | |
| SCHEMBL9220583 | 0.82 | TET2 (0.33) | CYP2D6TSHRCYP2C19HIF1A | |
| Acetic Acid SCHEMBL28559169 | 0.80 | FFAR3 (0.37) | ALDH1A1TDP1TSHRMEN1CYP1A2 | |
| SCHEMBL6516106 | 0.79 | TET2 (0.35) | — | |
| SCHEMBL17767286 | 0.77 | ALDH1A1 (0.38) | ALDH1A1TDP1MEN1CYP1A2THRB | |
| SCHEMBL17767284 | 0.77 | ALDH1A1 (0.38) | ALDH1A1TDP1MEN1CYP1A2THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0755927-B1 | DIMETHYLFURANCARBOXANILIDE DERIVATIVE | SANKYO CO (JP) | 2001-07-18 | — | — | EP | disclosed |