SCHEMBL7770902

SCHEMBL7770902

[N]=CC1C=Cc2cccc3cccc1c23

nearest known ligand 0.30

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.30
CYP1A1 P04798 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP3A4 P08684 1/20 0.30
HPGD P15428 1/20 0.30
TSHR P16473 1/20 0.30
CYP1B1 Q16678 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28960018 0.85 ALDH1A1 (0.32) ALDH1A1CYP1A1CYP1A2CYP3A4HPGD
SCHEMBL547797 0.82 ALDH1A1 (0.30) ALDH1A1CYP1A1CYP1A2CYP3A4HPGD
SCHEMBL27730862 0.82 ALDH1A1 (0.30) ALDH1A1CYP1A1CYP1A2CYP3A4HPGD
SCHEMBL3753725 0.82 MEN1 (0.30) ALDH1A1CYP1A1CYP1A2CYP3A4HPGD
SCHEMBL27515066 0.82 ALDH1A1 (0.30) ALDH1A1CYP1A1CYP1A2CYP3A4HPGD
SCHEMBL3267056 0.82 ALDH1A1 (0.30) ALDH1A1CYP1A1CYP1A2CYP3A4HPGD
SCHEMBL27973655 0.81
SCHEMBL28805395 0.78
SCHEMBL27496799 0.78
SCHEMBL27362350 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1132433-A2 Water-soluble fibre-reactive dyestuffs, process for their preparation and their use DyStar Textilfarben GmbH & Co. Deutschland KG (DE) 2001-09-12 EP claimed
EP-1127923-A2 Water-soluble fibre-reactive dyestuffs, process for their preparation and their use DyStar Textilfarben GmbH & Co. Deutschland KG (DE) 2001-08-29 EP claimed
EP-0848042-A2 Water-soluble fiber-reactive dyes, process for their preparation and the use thereof DyStar Textilfarben GmbH & Co. Deutschland KG (DE) 1998-06-17 EP claimed