Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | ESR1 | P03372 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7771125 | 1.00 | NQO2 (0.58) | NQO2LMNAMAPTESR1CYP3A4 | |
| SCHEMBL7121170 | 0.86 | NQO2 (0.56) | NQO2LMNAMAPTESR1CYP3A4 | |
| SCHEMBL7459982 | 0.86 | CPT1B (0.48) | NQO2LMNAMAPTESR1CYP3A4 | |
| SCHEMBL7121173 | 0.86 | NQO2 (0.56) | NQO2LMNAMAPTESR1CYP3A4 | |
| SCHEMBL7459978 | 0.86 | CPT1B (0.48) | NQO2LMNAMAPTESR1CYP3A4 | |
| SCHEMBL15708800 | 0.82 | CES2 (0.46) | NQO2MAPTKMT2AMEN1CYP1A2 | |
| SCHEMBL9244688 | 0.82 | TPMT (0.45) | NQO2CA2CA1PTPN1 | |
| SCHEMBL15708804 | 0.82 | CES2 (0.46) | NQO2MAPTKMT2AMEN1CYP1A2 | |
| SCHEMBL9244676 | 0.82 | TPMT (0.45) | NQO2CA2CA1PTPN1 | |
| SCHEMBL3670626 | 0.81 | CYP2C19 (0.50) | LMNAMAPTCYP3A4KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0825225-B1 | Rubber compositions containing n,n'-bis (hydroxyphenyl) maleamide | GOODYEAR TIRE & RUBBER (US) | 2001-07-11 | — | — | EP | disclosed |