Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL688159 | 0.74 | CYP3A4 (0.46) | ALDH1A1CYP3A4SMN1; SMN2 | |
| SCHEMBL8084872 | 0.72 | NQO1 (0.40) | ALDH1A1CYP3A4SMN1; SMN2 | |
| SCHEMBL6349570 | 0.64 | NQO2 (0.34) | — | |
| SCHEMBL5462155 | 0.64 | AOC3 (0.36) | CYP3A4AOC3 | |
| SCHEMBL1223125 | 0.63 | TSHR (0.32) | CYP3A4 | |
| SCHEMBL943239 | 0.62 | ABCG2 (0.33) | — | |
| SCHEMBL6222952 | 0.62 | TARBP2 (0.42) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL943947 | 0.61 | AOC3 (0.36) | AOC3 | |
| SCHEMBL944406 | 0.61 | ABCG2 (0.32) | — | |
| SCHEMBL6358713 | 0.60 | PLK1 (0.43) | ALDH1A1CYP3A4SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6248870-B1 | OLIGO-2,6-PYRIMIDINE COMPLEXING AGENT. | NYCOMED IMAGING AS (NO) | 2001-06-19 | — | — | US | disclosed |
| US-5817774-A | Unsymmetrical complexing agents and targeting immunoreagents useful in therapeutic and diagnostic compositions and methods | STERLING WINTHROP INCORPORATION (US) | 1998-10-06 | — | — | US | disclosed |
| US-5760191-A | Macrocyclic complexing agents and targeting immunoreagents useful in therapeutic and diagnostic compositions and methods | NYCOMED IMAGING AS (NO) | 1998-06-02 | — | — | US | disclosed |
| US-5559214-A | Unsymmetrical complexing agents and targeting immunoreagents useful in thearpeutic and diagnostic compositions and methods | STERLING WINTHROP INC. (US) | 1996-09-24 | — | — | US | disclosed |