Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11023512 | 0.83 | MEN1 (0.36) | — | |
| SCHEMBL14813317 | 0.79 | SMN1; SMN2 (0.37) | — | |
| SCHEMBL943239 | 0.76 | ABCG2 (0.33) | ABCG2 | |
| SCHEMBL6349570 | 0.74 | NQO2 (0.34) | ABCG2 | |
| SCHEMBL5462155 | 0.74 | AOC3 (0.36) | AOC3ABCG2 | |
| SCHEMBL944406 | 0.74 | ABCG2 (0.32) | ABCG2 | |
| SCHEMBL352094 | 0.74 | ABCG2 (0.32) | ABCG2 | |
| SCHEMBL688159 | 0.69 | CYP3A4 (0.46) | — | |
| SCHEMBL20906135 | 0.68 | XDH (0.44) | AOC3 | |
| SCHEMBL25166428 | 0.68 | MAPT (0.41) | AOC3ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8513260-B2 | Pyrazinylpyrazoles | BAYER CROPSCIENCE AG (DE) | 2013-08-20 | — | — | US | disclosed |
| EP-2435420-B1 | Pyrazinylpyrazoles | BAYER CROPSCIENCE AG (DE) | 2013-04-03 | — | — | EP | disclosed |
| US-20120190687-A1 | Pyrazinylpyrazoles | BAYER CROPSCIENCE AG | 2012-07-26 | — | — | US | disclosed |
| US-20110021539-A1 | Pyrazinylpyrazoles | BAYER CROPSCIENCE AG (DE) | 2011-01-27 | — | — | US | disclosed |
| EP-2266973-A1 | Pyrazinylpyrazole | Bayer CropScience AG (DE) | 2010-12-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110021539-A1 | Pyrazinylpyrazoles | CYP4F3, CYP4B1, CYP1A2 | AOC3 561/4885ABCG2 1777/4885 |
| US-20120190687-A1 | Pyrazinylpyrazoles | CYP4F3, CYP4B1, CYP1A2 | AOC3 561/4885ABCG2 1777/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.