SCHEMBL777192

SCHEMBL777192

CCOS(=O)(=O)OC(=O)c1cccc(C)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.46
HPGD P15428 1/20 0.46
PARP1 P09874 1/20 0.45
ADRB2 P07550 2/20 0.44
ADRB1 P08588 2/20 0.44
ADRB3 P13945 2/20 0.44
KMT2A Q03164 2/20 0.43
ALDH1A1 P00352 1/20 0.43
MAPK1 P28482 1/20 0.43
NPC1 O15118 1/20 0.43
RAB9A P51151 1/20 0.43
MEN1 O00255 1/20 0.43
ESR1 P03372 1/20 0.43
POLB P06746 1/20 0.43
ESR2 Q92731 1/20 0.43
HDAC8 Q9BY41 1/20 0.42
HDAC6 Q9UBN7 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
ELANE P08246 2/20 0.41
PKM P14618 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL779390 0.87 PARP1 (0.53) TDP1HPGDPARP1KMT2AALDH1A1
SCHEMBL778589 0.83 PARP1 (0.49) PARP1KMT2AMAPK1NPC1RAB9A
SCHEMBL28259576 0.83 SMPD1 (0.41) ALDH1A1HDAC8HDAC6
SCHEMBL777801 0.81 KMT2A (0.53) TDP1HPGDKMT2AALDH1A1NPC1
SCHEMBL27937494 0.79 PARP1 (0.52) TDP1HPGDPARP1KMT2AALDH1A1
SCHEMBL570920 0.79 TDP1 (0.60) TDP1HPGDPARP1ADRB2ADRB1
SCHEMBL29360475 0.79 TDP1 (0.60) TDP1HPGDPARP1ADRB2ADRB1
SCHEMBL27386628 0.78 TDP1 (0.54) TDP1ADRB2ADRB1ADRB3NPC1
SCHEMBL777882 0.78 SMN1; SMN2 (0.46) PARP1KMT2AALDH1A1MAPK1MEN1
SCHEMBL27503308 0.78 PARP1 (0.55) HPGDPARP1KMT2AMAPK1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9343777-B2 Non-aqueous liquid electrolyte and non-aqueous liquid electrolyte secondary battery MITSUBISHI CHEMICAL CORPORATION (JP) 2016-05-17 US disclosed
US-9252457-B2 Non-aqueous liquid electrolyte and non-aqueous liquid electrolyte secondary battery MITSUBISHI CHEMICAL CORPORATION (JP) 2016-02-02 US disclosed
US-20120177988-A1 NON-AQUEOUS LIQUID ELECTROLYTE AND NON-AQUEOUS LIQUID ELECTROLYTE SECONDARY BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2012-07-12 US disclosed
US-20120070731-A1 NON-AQUEOUS LIQUID ELECTROLYTE AND NON-AQUEOUS LIQUID ELECTROLYTE SECONDARY BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2012-03-22 US disclosed