SCHEMBL778589

SCHEMBL778589

COS(=O)(=O)OC(=O)c1cccc(C)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 1/20 0.49
HDAC8 Q9BY41 1/20 0.46
HDAC6 Q9UBN7 1/20 0.46
GPR17 Q13304 1/20 0.46
POLB P06746 3/20 0.46
KMT2A Q03164 3/20 0.46
ESR1 P03372 2/20 0.46
MEN1 O00255 1/20 0.46
ESR2 Q92731 1/20 0.46
NPC1 O15118 4/20 0.45
RAB9A P51151 4/20 0.45
SMN1; SMN2 Q16637 1/20 0.44
CTNNB1 P35222 2/20 0.43
TCF4 P15884 1/20 0.43
CYP1A2 P05177 1/20 0.43
CYP3A4 P08684 1/20 0.43
GAA P10253 1/20 0.43
MAPT P10636 1/20 0.43
CYP2C9 P11712 1/20 0.43
CYP2C19 P33261 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL779390 0.91 PARP1 (0.53) PARP1HDAC8HDAC6GPR17POLB
SCHEMBL27937494 0.83 PARP1 (0.52) PARP1HDAC8HDAC6POLBKMT2A
SCHEMBL777192 0.83 TDP1 (0.46) PARP1HDAC8HDAC6POLBKMT2A
SCHEMBL777882 0.81 SMN1; SMN2 (0.46) PARP1HDAC8HDAC6POLBKMT2A
SCHEMBL27808160 0.81 PARP1 (0.50) PARP1HDAC8HDAC6POLBKMT2A
SCHEMBL27503308 0.81 PARP1 (0.55) PARP1HDAC8HDAC6POLBKMT2A
SCHEMBL28259589 0.80 PARP1 (0.49) PARP1HDAC8HDAC6POLBKMT2A
SCHEMBL778426 0.79 TDP1 (0.59) KMT2AMEN1NPC1RAB9ASMN1; SMN2
SCHEMBL29534771 0.78 GPR17 (0.65) PARP1HDAC8HDAC6GPR17POLB
SCHEMBL40429 0.78 GPR17 (0.65) PARP1HDAC8HDAC6GPR17POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9343777-B2 Non-aqueous liquid electrolyte and non-aqueous liquid electrolyte secondary battery MITSUBISHI CHEMICAL CORPORATION (JP) 2016-05-17 US disclosed
US-9252457-B2 Non-aqueous liquid electrolyte and non-aqueous liquid electrolyte secondary battery MITSUBISHI CHEMICAL CORPORATION (JP) 2016-02-02 US disclosed
US-20120177988-A1 NON-AQUEOUS LIQUID ELECTROLYTE AND NON-AQUEOUS LIQUID ELECTROLYTE SECONDARY BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2012-07-12 US disclosed
US-20120070731-A1 NON-AQUEOUS LIQUID ELECTROLYTE AND NON-AQUEOUS LIQUID ELECTROLYTE SECONDARY BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2012-03-22 US disclosed