Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 19/20 | 0.46 |
| ▸ | RARA | P10276 | 4/20 | 0.46 |
| ▸ | RARB | P10826 | 4/20 | 0.46 |
| ▸ | RARG | P13631 | 4/20 | 0.46 |
| ▸ | RXRB | P28702 | 3/20 | 0.46 |
| ▸ | RXRG | P48443 | 3/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.37 |
| ▸ | HNF4A | P41235 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7771979 | 1.00 | RXRA (0.46) | RXRARARARARBRARGRXRB | |
| SCHEMBL7775631 | 0.87 | RXRA (0.52) | RXRARARARARBRARGRXRB | |
| SCHEMBL7775634 | 0.87 | RXRA (0.52) | RXRARARARARBRARGRXRB | |
| SCHEMBL7771885 | 0.84 | RXRA (0.70) | RXRARARARARBRARGRXRB | |
| SCHEMBL7771891 | 0.84 | RXRA (0.70) | RXRARARARARBRARGRXRB | |
| SCHEMBL7771888 | 0.84 | RXRA (0.70) | RXRARARARARBRARGRXRB | |
| SCHEMBL1140686 | 0.80 | RXRA (0.67) | RXRARARARARBRARGRXRB | |
| SCHEMBL728016 | 0.80 | RXRA (0.67) | RXRARARARARBRARGRXRB | |
| SCHEMBL728017 | 0.80 | RXRA (0.67) | RXRARARARARBRARGRXRB | |
| SCHEMBL8522363 | 0.78 | RXRA (0.37) | RXRARARARARBRARGPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0826657-B1 | Compounds for modulation of hormone receptors, compositions containing them and their use in therapy | CT INTERNAT DE RECH S (FR) | 2001-08-01 | — | — | EP | disclosed |
| EP-0826657-A1 | Compounds for modulation of hormone receptors, compositions containing them and their use in therapy | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA, ( CIRD GALDERMA) (FR) | 1998-03-04 | — | — | EP | disclosed |