⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29359980 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL311528 | 0.98 | RET (0.43) | — | |
| Hydrochloric Acid SCHEMBL310498 | 0.98 | RET (0.43) | — | |
| SCHEMBL30612360 | 0.98 | RET (0.43) | — | |
| Water SCHEMBL438450 | 0.98 | RET (0.43) | — | |
| SCHEMBL3882735 | 0.89 | RET (0.38) | — | |
| Acetamide SCHEMBL9934182 | 0.86 | PIK3C3 (0.38) | — | |
| SCHEMBL30202633 | 0.82 | — | — | |
| SCHEMBL32668610 | 0.79 | — | — | |
| SCHEMBL30495986 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 4789 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12545682-B2 | Heterocyclic derivatives as P2X7 receptor antagonists | BREYE THERAPEUTICS APS (DK) | 2026-02-10 | — | — | US | claimed |
| US-20250388599-A1 | TRICYCLIC PI3K INHIBITOR COMPOUNDS AND METHODS OF USE | GENENTECH INC (US) | 2025-12-25 | — | — | US | claimed |
| EP-3590516-B1 | ANTITUMOR-EFFECT ENHANCER USING PYRAZOLO[3,4-D]PYRIMIDINE COMPOUND | TAIHO PHARMACEUTICAL CO LTD (JP) | 2025-09-03 | — | — | EP | claimed |
| WO-2025111482-A1 | COMPLEXING AGENT SALT FORMULATIONS OF PHARMACEUTICAL COMPOUNDS AT LOW STOICHIOMETRIC RATIOS | BEXSON BIOMEDICAL, INC. (US) | 2025-05-30 | — | — | WO | claimed |
| EP-4090332-B1 | COMPOSITIONS OF SUBSTITUTED PYRAZOLOPYRIMIDINES AND USES THEREOF | KSQ THERAPEUTICS INC (US) | 2025-03-12 | — | — | EP | claimed |
| EP-4262975-B1 | HETEROCYCLIC DERIVATIVES AS P2X7 RECEPTOR ANTAGONISTS | BREYE THERAPEUTICS APS (DK) | 2025-03-05 | — | — | EP | claimed |
| US-12186320-B2 | Therapeutic agent containing pyrazolo[3,4-d]pyrimidine compound as active ingredient | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2025-01-07 | — | — | US | claimed |
| EP-3845231-B1 | THERAPEUTIC AGENT CONTAINING PYRAZOLO[3,4-D]PYRIMIDINE COMPOUND AS ACTIVE INGREDIENT | TAIHO PHARMACEUTICAL CO LTD (JP) | 2025-01-01 | — | — | EP | claimed |
| WO-2024175999-A2 | BENZENESULFONAMIDE DERIVATIVES AND USES THEREOF | DUNAD THERAPEUTICS LTD. (GB) | 2024-08-29 | — | — | WO | claimed |
| WO-2024175998-A1 | BENZENESULFONAMIDE DERIVATIVES AND USES THEREOF | DUNAD THERAPEUTICS, LTD. (GB) | 2024-08-29 | — | — | WO | claimed |
| WO-1990003370-A1 | DERIVATIVES OF PYRAZOLO[3,4-d]PYRIMIDINE | MICROPROBE CORPORATION (US) | 1990-04-05 | — | — | WO | claimed |
| US-4904666-A | Pyrazolo(3,4-d)pyrimidine compounds, compositions and method of use | BOEHRINGER MANNHEIM GMBH (DE) | 1990-02-27 | — | — | US | claimed |
| US-4871653-A | DEVELOPING IN PRESENCE OF MERCAPTO POLYAZAINDENE PROMOTERS AND NUCLEATING QUATERNARY OR HYDRAZIDE-TYPE COMPOUNDS | FUJI PHOTO FILM CO., LTD. (JP) | 1989-10-03 | — | — | US | claimed |
| US-4511557-A | CALF'S BLOOD DIAYSATE AS VASODILATION POTENTIATOR | GAURI KAILASH KUMAR (DE) | 1985-04-16 | — | — | US | claimed |
| EP-0106309-A2 | Biologically active extracts, process for their manufacture, medicinal and cosmetical preparations comprising them, and their use as additives in foodstuffs and stimulants | Gauri, Kailash Kumar, Dr. Prof. (DE) | 1984-04-25 | — | — | EP | claimed |
| EP-0077372-A1 | NEW DERIVATIVES OF PYRAZOLO(3,4-d)PYRIMIDINE, PREPARATION METHOD THEREOF AND REMEDY CONTAINING THEM | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1983-04-27 | — | — | EP | claimed |
| WO-1982003626-A1 | NEW DERIVATIVES OF PYRAZOLO(3,4-D)PYRIMIDINE,PREPARATION METHOD THEREOF AND REMEDY CONTAINING THEM | GAURI KAILASH KUMAR | 1982-10-28 | — | — | WO | claimed |
| EP-0063381-A1 | Pyrazolo(3-4-d) pyrimidines, process for their preparation and pharmaceutical compositions containing them | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1982-10-27 | — | — | EP | claimed |
| US-4286093-A | 9-Cyclohexyl-2-alkoxy-9H-adenine process | MEAD JOHNSON & COMPANY (US) | 1981-08-25 | — | — | US | claimed |
| US-4001230-A | ANTIBACTERIAL, ANTIPROTAZOAL | ELI LILLY AND COMPANY (US) | 1977-01-04 | — | — | US | claimed |