Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 10/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | DRD4 | P21917 | 2/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21114120 | 0.85 | KDM4E (0.40) | LSSMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL21113981 | 0.81 | LSS (0.41) | LSSMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL7685790 | 0.81 | LSS (0.64) | LSSMEN1KMT2A | |
| SCHEMBL7685786 | 0.81 | LSS (0.64) | LSSMEN1KMT2A | |
| SCHEMBL7764181 | 0.80 | KDM4E (0.39) | LSSKDM4EALDH1A1DRD4DRD2 | |
| SCHEMBL7768887 | 0.79 | KDM4E (0.39) | LSSMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL8045180 | 0.77 | LSS (0.66) | LSSMEN1KMT2AKDM4EALDH1A1 | |
| Fumaric Acid SCHEMBL7685326 | 0.77 | LSS (0.69) | LSSMEN1KMT2A | |
| Fumaric Acid SCHEMBL7685337 | 0.77 | LSS (0.69) | LSSMEN1KMT2A | |
| SCHEMBL21163136 | 0.75 | LSS (0.43) | LSSMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0778264-B1 | Tertiary amines having antimycotic and cholesterol lowering activity | HOFFMANN LA ROCHE (CH) | 2001-07-11 | — | — | EP | claimed |