Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LSS | P48449 | 5/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | DRD4 | P21917 | 2/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7768887 | 0.89 | KDM4E (0.39) | KDM4EALDH1A1LSSTP53GAA | |
| SCHEMBL7677304 | 0.80 | LSS (0.62) | LSS | |
| SCHEMBL7772051 | 0.80 | LSS (0.41) | KDM4EALDH1A1LSSTP53GAA | |
| SCHEMBL7768117 | 0.76 | LSS (0.65) | KDM4EALDH1A1LSSLMNA | |
| SCHEMBL8035143 | 0.72 | LSS (0.60) | KDM4EALDH1A1LSSDRD4DRD2 | |
| SCHEMBL7767773 | 0.71 | LSS (0.52) | KDM4EALDH1A1LSSLMNA | |
| SCHEMBL7769052 | 0.70 | LSS (0.39) | KDM4EALDH1A1LSSGAANPC1 | |
| SCHEMBL8045180 | 0.69 | LSS (0.66) | KDM4EALDH1A1LSSLMNA | |
| SCHEMBL7685895 | 0.69 | LSS (0.56) | LSS | |
| SCHEMBL7685893 | 0.69 | LSS (0.56) | LSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0778264-B1 | Tertiary amines having antimycotic and cholesterol lowering activity | HOFFMANN LA ROCHE (CH) | 2001-07-11 | — | — | EP | claimed |