Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | TACR1 | P25103 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | FPR1 | P21462 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7380302 | 0.81 | NPC1 (0.48) | KDM4EALDH1A1MAPK1RCE1SMN1; SMN2 | |
| SCHEMBL7773550 | 0.77 | F2 (0.48) | KDM4EALDH1A1MAPK1RCE1SMN1; SMN2 | |
| SCHEMBL8123909 | 0.77 | CYP1A2 (0.45) | KDM4EALDH1A1MAPK1RCE1SMN1; SMN2 | |
| SCHEMBL7377097 | 0.76 | KDM4E (0.44) | KDM4EALDH1A1MAPK1RCE1SMN1; SMN2 | |
| SCHEMBL7773547 | 0.75 | SMN1; SMN2 (0.43) | KDM4EALDH1A1MAPK1RCE1SMN1; SMN2 | |
| SCHEMBL7376547 | 0.74 | METAP2 (0.44) | KDM4EALDH1A1MAPK1RCE1KMT2A | |
| SCHEMBL7767810 | 0.72 | PTGDR2 (0.42) | MAPK1LMNARAB9AMAPT | |
| SCHEMBL8817030 | 0.69 | LCK (0.65) | KDM4EALDH1A1SMN1; SMN2LMNAKMT2A | |
| SCHEMBL7371665 | 0.68 | F2 (0.49) | F2 | |
| SCHEMBL7376688 | 0.68 | F2 (0.42) | KDM4EALDH1A1MAPK1RCE1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6252082-B1 | CARDIOVASCUALR DISORDERS | SANOFI-SYNTHELABO (FR) | 2001-06-26 | — | — | US | disclosed |