Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 17/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14727255 | 0.83 | TSHR (0.42) | LSSTSHR | |
| SCHEMBL7354444 | 0.78 | LSS (0.38) | LSSTSHR | |
| SCHEMBL21533190 | 0.77 | TSHR (0.48) | TSHR | |
| SCHEMBL28230743 | 0.77 | TSHR (0.48) | TSHR | |
| SCHEMBL9805588 | 0.77 | DNM1 (0.48) | LSSTSHR | |
| SCHEMBL9805638 | 0.77 | DNM1 (0.48) | LSSTSHR | |
| SCHEMBL8775557 | 0.77 | DNM1 (0.48) | LSSTSHR | |
| SCHEMBL9805609 | 0.77 | DNM1 (0.48) | LSSTSHR | |
| SCHEMBL7373843 | 0.77 | DNM1 (0.48) | LSSTSHR | |
| SCHEMBL11559689 | 0.77 | DNM1 (0.48) | LSSTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0778264-B1 | Tertiary amines having antimycotic and cholesterol lowering activity | HOFFMANN LA ROCHE (CH) | 2001-07-11 | — | — | EP | disclosed |
| US-6034275-A | FUGICIDES; ATICHOLESTEROL AGENTS | HOFFMANN-LA ROCHE INC. (US) | 2000-03-07 | — | — | US | disclosed |
| EP-0778264-A1 | Tertiary amines having antimycotic and cholesterol lowering activity | F. HOFFMANN-LA ROCHE AG (CH) | 1997-06-11 | — | — | EP | disclosed |