Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.36 |
| ▸ | ALPL | P05186 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CYTH3 | O43739 | 1/20 | 0.34 |
| ▸ | BTK | Q06187 | 1/20 | 0.34 |
| ▸ | EPN1 | Q9Y6I3 | 1/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12694613 | 0.81 | BAZ2B (0.41) | MEN1KMT2AHDAC3HDAC4HDAC1 | |
| SCHEMBL4708946 | 0.75 | — | — | |
| SCHEMBL930682 | 0.75 | — | — | |
| SCHEMBL19185146 | 0.75 | MAOB (0.46) | MEN1KMT2AHDAC3HDAC4HDAC1 | |
| SCHEMBL2049762 | 0.75 | HPGD (0.52) | RAB9ANPC1HPGD | |
| SCHEMBL19638915 | 0.74 | HDAC3 (0.47) | KMT2AHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL12270026 | 0.74 | — | — | |
| SCHEMBL1009738 | 0.73 | MAPK1 (0.65) | MEN1KMT2AALPLMAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL17512686 | 0.73 | HDAC3 (0.46) | KMT2AHDAC3HDAC4HDAC1HDAC7 | |
| Hydrochloric Acid SCHEMBL14785045 | 0.72 | MAPK1 (0.62) | MEN1KMT2AALPLMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1131300-A2 | METHOD FOR PRODUCING 5-AMINO-3-(THIO)CARBAMOYLPYRAZOLES | Bayer Aktiengesellschaft (DE) | 2001-09-12 | — | — | EP | claimed |
| WO-2000031043-A2 | METHOD FOR PRODUCING 5-AMINO-3-(THIO)CARBAMOYLPYRAZOLES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-06-02 | — | — | WO | claimed |
| CN-1326446-A | Method for producing 5-Amino-3-(thio) carbamoylpyrazoles | BAYER AG (DE) | 2001-12-12 | — | — | CN | disclosed |
| EP-1131300-A2 | METHOD FOR PRODUCING 5-AMINO-3-(THIO)CARBAMOYLPYRAZOLES | Bayer Aktiengesellschaft (DE) | 2001-09-12 | — | — | EP | disclosed |
| EP-1131300-A2 | METHOD FOR PRODUCING 5-AMINO-3-(THIO)CARBAMOYLPYRAZOLES | Bayer Aktiengesellschaft (DE) | 2001-09-12 | — | — | EP | disclosed |
| WO-2000031043-A3 | METHOD FOR PRODUCING 5-AMINO-3-(THIO)CARBAMOYLPYRAZOLES | BAYER AG (DE) | 2000-11-09 | — | — | WO | disclosed |
| WO-2000031043-A2 | METHOD FOR PRODUCING 5-AMINO-3-(THIO)CARBAMOYLPYRAZOLES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-06-02 | — | — | WO | disclosed |
| WO-2000031043-A2 | METHOD FOR PRODUCING 5-AMINO-3-(THIO)CARBAMOYLPYRAZOLES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-06-02 | — | — | WO | disclosed |