SCHEMBL7772673

SCHEMBL7772673

C=COC(=O)c1ccoc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 1/20 0.47
PTPN6 P29350 1/20 0.47
PTPN11 Q06124 1/20 0.47
RAB9A P51151 3/20 0.43
NPC1 O15118 2/20 0.43
MAPT P10636 4/20 0.41
MEN1 O00255 2/20 0.40
CYP1A2 P05177 2/20 0.40
CYP2C19 P33261 2/20 0.40
KMT2A Q03164 2/20 0.40
ALDH1A1 P00352 2/20 0.40
HPGD P15428 2/20 0.40
KDM4E B2RXH2 1/20 0.40
CYP2D6 P10635 1/20 0.40
CYP2C9 P11712 1/20 0.40
TRPA1 O75762 1/20 0.39
CYP3A4 P08684 1/20 0.38
RECQL P46063 1/20 0.37
GPR52 Q9Y2T5 1/20 0.37
HCAR2 Q8TDS4 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27533173 0.82 PTPN1 (0.49) PTPN1PTPN6PTPN11RAB9ANPC1
SCHEMBL8853764 0.82 PTPN1 (0.43) PTPN1PTPN6PTPN11RAB9ANPC1
SCHEMBL14359816 0.78 PTPN1 (0.45) PTPN1PTPN6PTPN11RAB9ANPC1
SCHEMBL14359812 0.78 PTPN1 (0.45) PTPN1PTPN6PTPN11RAB9ANPC1
SCHEMBL6966817 0.78
SCHEMBL8778642 0.77 PTPN1 (0.55) PTPN1PTPN6PTPN11RAB9ANPC1
SCHEMBL7772581 0.77 MAPT (0.34) PTPN1PTPN6PTPN11RAB9ANPC1
SCHEMBL295796 0.77 ALDH1A1 (0.40) MAPTMEN1KMT2AALDH1A1F2
SCHEMBL6545751 0.77 CYP3A4 (0.51) PTPN1PTPN6PTPN11RAB9ANPC1
SCHEMBL28944014 0.74 ALDH1A1 (0.39) MAPTMEN1KMT2AALDH1A1F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0711813-B1 Antifouling coating composition HITACHI CHEMICAL CO LTD (JP) 2001-07-25 EP disclosed
US-5773508-A BIODEGRADABLE POLYMER OF ADDITION COPOLYMERS FOR PROTECTIVE COATINGS HITACHI CHEMICAL COMPANY, LTD. (JP) 1998-06-30 US disclosed
EP-0711813-A2 Coating varnish composition and antifouling coating composition Hitachi Chemical Co., Ltd. (JP) 1996-05-15 EP disclosed