Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Monoethanolamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Monoethanolamine SCHEMBL8518108 | 0.95 | CYP2D6 (0.50) | CYP2D6ALDH1A1TSHRKDM4E | |
| SCHEMBL24257 | 0.86 | — | — | |
| Hydrochloric Acid SCHEMBL780231 | 0.83 | — | — | |
| Ammonia Solution, Strong SCHEMBL6516228 | 0.83 | — | — | |
| Ethylamine SCHEMBL7773007 | 0.80 | CYP2D6 (0.41) | CYP2D6KDM4E | |
| Ethylamine SCHEMBL7773015 | 0.80 | CYP2D6 (0.41) | CYP2D6KDM4E | |
| Monoethanolamine SCHEMBL27776023 | 0.77 | ALDH1A1 (0.53) | CYP2D6ALDH1A1TSHRKDM4E | |
| SCHEMBL8518107 | 0.77 | CYP2D6 (0.43) | CYP2D6KDM4E | |
| Monoethanolamine SCHEMBL5730563 | 0.76 | — | — | |
| Propylamine SCHEMBL27912341 | 0.75 | CYP2D6 (0.37) | CYP2D6ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1068276-A1 | RF ACTIVE COMPOSITIONS FOR USE IN ADHESION, BONDING AND COATING | Ameritherm, Inc. (US) | 2001-01-17 | — | — | EP | disclosed |
| WO-1999047621-A1 | RF ACTIVE COMPOSITIONS FOR USE IN ADHESION, BONDING AND COATING | AMERITHERM, INC. (US) | 1999-09-23 | — | — | WO | disclosed |