SCHEMBL7773552

SCHEMBL7773552

CCCCC(=O)Oc1ccc(C(=O)O)c(N)c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.54
KMT2A Q03164 3/20 0.54
MEN1 O00255 1/20 0.54
RECQL P46063 1/20 0.54
CA2 P00918 5/20 0.46
MAPT P10636 2/20 0.42
TP53 P04637 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.41
GABRP O00591 1/20 0.40
GABRD O14764 1/20 0.40
GABRA1 P14867 1/20 0.40
GABRB1 P18505 1/20 0.40
GABRG2 P18507 1/20 0.40
GABRB3 P28472 1/20 0.40
GABRA5 P31644 1/20 0.40
GABRA3 P34903 1/20 0.40
GABRA2 P47869 1/20 0.40
GABRB2 P47870 1/20 0.40
GABRA4 P48169 1/20 0.40
GABRE P78334 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7773613 0.91 CA2 (0.47) KDM4EKMT2AMEN1RECQLCA2
SCHEMBL7781084 0.85 ESR1 (0.49) KDM4EKMT2ARECQLSMN1; SMN2ALDH1A1
SCHEMBL11639642 0.82 KMT2A (0.47) KDM4EKMT2AMEN1RECQLCA2
SCHEMBL4256831 0.82 PTPN11 (0.55) TP53RARARARB
SCHEMBL11708640 0.80 KMT2A (0.50) KDM4EKMT2AMEN1RECQLCA2
SCHEMBL7773557 0.79 PTPN11 (0.59) TP53RARB
SCHEMBL7764445 0.79 RARB (0.53) KDM4EKMT2AMEN1RECQLCA2
SCHEMBL13274098 0.78 CA2 (0.44) KDM4EKMT2AMEN1RECQLCA2
SCHEMBL7778432 0.78 ELANE (0.48) KDM4EKMT2AALDH1A1HSD17B10HPGD
SCHEMBL8183565 0.78 PTPN11 (0.61) TP53RARB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0781767-B1 Process for producing isatoic anhydrides SUMITOMO CHEMICAL CO (JP) 2001-09-05 EP disclosed
US-5981749-A Process for producing isatoic anhydrides SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1999-11-09 US disclosed
US-5973145-A Process for producing isatoic anhydrides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-10-26 US disclosed
US-5795984-A Process for producing isatoic anhydrides SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1998-08-18 US disclosed
EP-0781767-A1 Process for producing isatoic anhydrides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-07-02 EP disclosed