Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of (Phenylsulfonyl)Benzene. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 3/20 | 0.82 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA3 | P07451 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
| ▸ | CA6 | P23280 | 1/20 | 0.50 |
| ▸ | CA5A | P35218 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| (Phenylsulfonyl)Benzene SCHEMBL28237512 | 0.94 | HTR6 (0.93) | HTR6SMN1; SMN2TSHRHPGDMEN1 | |
| (Phenylsulfonyl)Benzene SCHEMBL9642349 | 0.92 | HTR6 (0.78) | HTR6SMN1; SMN2TSHRHPGDMEN1 | |
| (Phenylsulfonyl)Benzene SCHEMBL28119187 | 0.91 | HTR6 (1.00) | HTR6SMN1; SMN2TSHRCA1CA2 | |
| (Phenylsulfonyl)Benzene SCHEMBL29473549 | 0.91 | HTR6 (1.00) | HTR6SMN1; SMN2TSHRCA1CA2 | |
| (Phenylsulfonyl)Benzene SCHEMBL13735236 | 0.91 | HTR6 (1.00) | HTR6SMN1; SMN2TSHRCA1CA2 | |
| (Phenylsulfonyl)Benzene SCHEMBL29450723 | 0.91 | HTR6 (1.00) | HTR6SMN1; SMN2TSHRCA1CA2 | |
| (Phenylsulfonyl)Benzene SCHEMBL29775288 | 0.91 | HTR6 (1.00) | HTR6SMN1; SMN2TSHRCA1CA2 | |
| (Phenylsulfonyl)Benzene SCHEMBL30255 | 0.91 | HTR6 (1.00) | HTR6SMN1; SMN2TSHRCA1CA2 | |
| (Phenylsulfonyl)Benzene SCHEMBL29058880 | 0.89 | HTR6 (0.74) | HTR6SMN1; SMN2TSHRHPGDMEN1 | |
| (Phenylsulfonyl)Benzene SCHEMBL8958296 | 0.89 | HTR6 (0.74) | HTR6SMN1; SMN2TSHRHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-220478125-U | Retrieve device of carbonic acid diphenyl sulfone catalyst | 江苏新瀚新材料股份有限公司 | 2024-02-13 | — | — | CN | claimed |
| EP-0683200-B1 | Stabilizer composition | GEN ELECTRIC (US) | 2001-09-26 | — | — | EP | claimed |
| EP-0369200-A2 | Low gloss molded article using polyorganosiloxane/polyvinyl-based graft polymers | GENERAL ELECTRIC COMPANY (US) | 1990-05-23 | — | — | EP | claimed |
| CN-220478125-U | Retrieve device of carbonic acid diphenyl sulfone catalyst | 江苏新瀚新材料股份有限公司 | 2024-02-13 | — | — | CN | disclosed |
| CN-220478125-U | Retrieve device of carbonic acid diphenyl sulfone catalyst | 江苏新瀚新材料股份有限公司 | 2024-02-13 | — | — | CN | disclosed |
| CN-220478125-U | Retrieve device of carbonic acid diphenyl sulfone catalyst | 江苏新瀚新材料股份有限公司 | 2024-02-13 | — | — | CN | disclosed |
| EP-0683200-B1 | Stabilizer composition | GEN ELECTRIC (US) | 2001-09-26 | — | — | EP | disclosed |
| US-5608027-A | HEAT STABLE OR COLORFASTNESS | GENERAL ELECTRIC COMPANY (US) | 1997-03-04 | — | — | US | disclosed |
| EP-0683200-A1 | Stabilizer composition | GENERAL ELECTRIC COMPANY (US) | 1995-11-22 | — | — | EP | disclosed |
| EP-0369200-A2 | Low gloss molded article using polyorganosiloxane/polyvinyl-based graft polymers | GENERAL ELECTRIC COMPANY (US) | 1990-05-23 | — | — | EP | disclosed |
| US-4927880-A | FLATTING AGENT | GENERAL ELECTRIC COMPANY (US) | 1990-05-22 | — | — | US | disclosed |