Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7774351 | 1.00 | HTR2C (0.31) | HTR2CTHRBTBXAS1KDM1ARCOR1 | |
| SCHEMBL7781540 | 0.86 | KDM1A (0.33) | HTR2CTBXAS1KDM1ARCOR1 | |
| SCHEMBL7781543 | 0.86 | KDM1A (0.33) | HTR2CTBXAS1KDM1ARCOR1 | |
| SCHEMBL7774288 | 0.85 | MEN1 (0.31) | — | |
| SCHEMBL7774293 | 0.85 | MEN1 (0.31) | — | |
| SCHEMBL7778836 | 0.84 | TBXAS1 (0.34) | TBXAS1KDM1ARCOR1 | |
| SCHEMBL7778832 | 0.84 | TBXAS1 (0.34) | TBXAS1KDM1ARCOR1 | |
| SCHEMBL7774565 | 0.80 | HTR2C (0.32) | HTR2CTBXAS1KDM1ARCOR1 | |
| SCHEMBL7774560 | 0.80 | HTR2C (0.32) | HTR2CTBXAS1KDM1ARCOR1 | |
| SCHEMBL7774562 | 0.80 | HTR2C (0.32) | HTR2CTBXAS1KDM1ARCOR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0732330-B1 | Di-1,3-dioxane derivatives useful as liquid crystals | ROLIC AG (CH) | 2001-09-12 | — | — | EP | disclosed |
| US-5667721-A | Liquid crystalline di-1,3-dioxane derivatives | ROLIC AG (CH) | 1997-09-16 | — | — | US | disclosed |
| EP-0732330-A1 | Di-1,3-dioxane derivatives useful as liquid crystals | F. HOFFMANN-LA ROCHE AG (CH) | 1996-09-18 | — | — | EP | disclosed |