Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.65 |
| ▸ | RAB9A | P51151 | 8/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.65 |
| ▸ | HPGD | P15428 | 3/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.61 |
| ▸ | CASP1 | P29466 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | RELA | Q04206 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7774579 | 1.00 | NPC1 (0.65) | NPC1RAB9ASMN1; SMN2HPGDL3MBTL1 | |
| SCHEMBL6819635 | 1.00 | NPC1 (0.65) | NPC1RAB9ASMN1; SMN2HPGDL3MBTL1 | |
| SCHEMBL27701440 | 0.94 | RAB9A (0.73) | NPC1RAB9ASMN1; SMN2HPGDL3MBTL1 | |
| SCHEMBL11133582 | 0.93 | NPC1 (0.58) | NPC1RAB9ASMN1; SMN2HPGDL3MBTL1 | |
| SCHEMBL11138867 | 0.93 | NPC1 (0.58) | NPC1RAB9ASMN1; SMN2HPGDL3MBTL1 | |
| SCHEMBL10895369 | 0.93 | NPC1 (0.58) | NPC1RAB9ASMN1; SMN2HPGDL3MBTL1 | |
| SCHEMBL12411578 | 0.92 | RAB9A (0.69) | NPC1RAB9ASMN1; SMN2HPGDL3MBTL1 | |
| SCHEMBL8378649 | 0.88 | NPC1 (0.69) | NPC1RAB9ASMN1; SMN2HPGDL3MBTL1 | |
| SCHEMBL12723978 | 0.88 | TSHR (0.67) | NPC1RAB9ASMN1; SMN2HPGDL3MBTL1 | |
| SCHEMBL2070195 | 0.87 | SMN1; SMN2 (0.71) | NPC1RAB9ASMN1; SMN2HPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832757-B1 | REVERSIBLE THERMAL RECORDING MEDIUM | OJI PAPER CO (JP) | 2001-08-22 | — | — | EP | disclosed |
| US-5928988-A | CONTAINING SULFONYLUREA COLOR DEVELOPER | OJI PAPER CO., LTD. (JP) | 1999-07-27 | — | — | US | disclosed |
| EP-0832757-A1 | REVERSIBLE THERMAL RECORDING MEDIUM | Oji Paper Co., Ltd. (JP) | 1998-04-01 | — | — | EP | disclosed |