Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.34 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.33 |
| ▸ | CPN1 | P15169 | 1/20 | 0.32 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1159969 | 0.81 | PDE4A (0.50) | PDE4AOR51E2USP2SLCO1B1LMNA | |
| SCHEMBL5489376 | 0.78 | PTGS1 (0.37) | PTGS1SLC7A11TDP1ENPEPFOLH1 | |
| SCHEMBL3064781 | 0.75 | PDE4A (0.44) | PDE4AOR51E2USP2SLCO1B1LMNA | |
| SCHEMBL3073651 | 0.75 | PDE4A (0.44) | PDE4AOR51E2USP2SLCO1B1LMNA | |
| SCHEMBL21143414 | 0.75 | TDP1 (0.62) | PDE4AOR51E2USP2SLCO1B1LMNA | |
| SCHEMBL1895730 | 0.75 | PDE4A (0.44) | PDE4AOR51E2USP2SLCO1B1LMNA | |
| SCHEMBL3064788 | 0.75 | PDE4A (0.44) | PDE4AOR51E2USP2SLCO1B1LMNA | |
| SCHEMBL3847707 | 0.73 | PTGS1 (0.37) | PTGS1SLC7A11LMNATDP1ENPEP | |
| SCHEMBL2142946 | 0.72 | — | — | |
| Dithioerythriol SCHEMBL7523387 | 0.71 | PDE4A (0.37) | PDE4AOR51E2USP2SLCO1B1PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2001501534-A | — | — | 2001-02-06 | — | — | JP | claimed |
| EP-0929585-A1 | CATALYSTS | TIOXIDE SPECIALTIES LIMITED (GB) | 1999-07-21 | — | — | EP | claimed |
| WO-1998015585-A1 | CATALYSTS | TIOXIDE SPECIALTIES LIMITED (GB) | 1998-04-16 | — | — | WO | claimed |
| EP-0929585-A1 | CATALYSTS | TIOXIDE SPECIALTIES LIMITED (GB) | 1999-07-21 | — | — | EP | disclosed |
| WO-1998015585-A1 | CATALYSTS | TIOXIDE SPECIALTIES LIMITED (GB) | 1998-04-16 | — | — | WO | disclosed |