SCHEMBL5489376

SCHEMBL5489376

CCC(O)C(CS)C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.37
SLC7A11 Q9UPY5 1/20 0.37
MME P08473 1/20 0.36
KDM4E B2RXH2 1/20 0.35
MAPT P10636 1/20 0.35
THRB P10828 1/20 0.35
ALOX15 P16050 1/20 0.35
NFKB1 P19838 1/20 0.35
PTGS2 P35354 1/20 0.35
THPO P40225 1/20 0.35
RECQL P46063 1/20 0.35
BLM P54132 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
ENPEP Q07075 4/20 0.34
TP53 P04637 1/20 0.33
ACE P12821 1/20 0.32
FOLH1 Q04609 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL687714 0.82 TDP1 (0.42) TDP1TP53
SCHEMBL3837519 0.82 TDP1 (0.42) TDP1TP53
SCHEMBL27677822 0.78 OR51E2 (0.42) TDP1TP53
SCHEMBL7775006 0.78 PDE4A (0.44) PTGS1SLC7A11KDM4EMAPTTHRB
SCHEMBL13986496 0.76 TDP1 (0.48) MAPTNFKB1TDP1
SCHEMBL1000793 0.76 TDP1 (0.48) MAPTNFKB1TDP1
SCHEMBL9636422 0.76 TDP1 (0.48) MAPTNFKB1TDP1
SCHEMBL2969410 0.76 ACE (0.46) PTGS1SLC7A11MMEKDM4EMAPT
SCHEMBL29071614 0.76 TDP1 (0.37) PTGS1SLC7A11MMEKDM4EMAPT
SCHEMBL28035406 0.76 TDP1 (0.59) MAPTSMN1; SMN2TDP1TP53FOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7238386-B2 Methods for making and using point lump-free compositions and products coated with point lump-free compositions HEXION SPECIALTY CHEMICALS, INC. (US) 2007-07-03 US disclosed
EP-1503970-A4 METHODS FOR MAKING AND USING POINT LUMP-FREE COMPOSITIONS AND PRODUCTS COATED WITH POINT LUMP-FREE COMPOSITIONS BORDEN CHEM INC (US) 2006-01-18 EP disclosed
EP-1503970-A1 METHODS FOR MAKING AND USING POINT LUMP-FREE COMPOSITIONS AND PRODUCTS COATED WITH POINT LUMP-FREE COMPOSITIONS BORDEN CHEMICAL, INC. (US) 2005-02-09 EP disclosed
WO-2003095387-A1 METHODS FOR MAKING AND USING POINT LUMP-FREE COMPOSITIONS AND PRODUCTS COATED WITH POINT LUMP-FREE COMPOSITIONS BORDEN CHEMICAL, INC. (US) 2003-11-20 WO disclosed
US-20030211236-A1 Methods for making and using point lump-free composions and products coated with point lump-free compositions Westlake Epoxy Inc. 2003-11-13 US disclosed
EP-0745570-B1 Ultraviolet radiation-curable coatings for optical fibres and optical fibres coated therewith BORDEN CHEM INC (US) 2003-04-02 EP disclosed
EP-0565798-B2 Ultraviolet radiation-curable coatings for optical fibers and optical fibers coated therewith BORDEN CHEM INC (US) 2001-03-07 EP disclosed
EP-0565798-B1 Ultraviolet radiation-curable coatings for optical fibers and optical fibers coated therewith BORDEN INC (US) 1998-01-14 EP disclosed
US-5639846-A BASED ON A REACTIVELY TERMINATED URETHANE OLIGOMER AND A HYDROCARBON MONOMER TERMINATED WITH AN END GROUP CAPABLE OF REACTING WITH THE TERMINUS OF THE OLIGOMER BORDEN, INC. (US) 1997-06-17 US disclosed
EP-0745570-A2 Ultraviolet radiation-curable coatings for optical fibres and optical fibres coated therewith Borden, Inc. (US) 1996-12-04 EP disclosed
US-5536529-A Ultraviolet radiation-curable coatings for optical fibers and optical fibers coated therewith BORDEN, INC. (US) 1996-07-16 US disclosed
US-5352712-A Modified polyurethane BORDEN, INC. (US) 1994-10-04 US disclosed
EP-0565798-A1 Ultraviolet radiation-curable coatings for optical fibers and optical fibers coated therewith BORDEN, INC. (US) 1993-10-20 EP disclosed