Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | ANPEP | P15144 | 1/20 | 0.47 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 7/20 | 0.43 |
| ▸ | ADH1B | P00325 | 2/20 | 0.43 |
| ▸ | ADH1C | P00326 | 2/20 | 0.43 |
| ▸ | ADH1A | P07327 | 2/20 | 0.43 |
| ▸ | ADH4 | P08319 | 2/20 | 0.43 |
| ▸ | ADH7 | P40394 | 2/20 | 0.43 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 5/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.39 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20134437 | 1.00 | TSHR (0.52) | TSHRALDH1A1ANPEPERAP2EPHX1 | |
| SCHEMBL20281606 | 1.00 | TSHR (0.52) | TSHRALDH1A1ANPEPERAP2EPHX1 | |
| SCHEMBL7778097 | 1.00 | TSHR (0.52) | TSHRALDH1A1ANPEPERAP2EPHX1 | |
| SCHEMBL10000678 | 1.00 | TSHR (0.52) | TSHRALDH1A1ANPEPERAP2EPHX1 | |
| SCHEMBL20706483 | 1.00 | TSHR (0.52) | TSHRALDH1A1ANPEPERAP2EPHX1 | |
| Hydrochloric Acid SCHEMBL11121260 | 0.98 | TSHR (0.50) | TSHRALDH1A1ANPEPERAP2EPHX1 | |
| SCHEMBL7775105 | 0.98 | TSHR (0.55) | TSHRALDH1A1ANPEPERAP2EPHX1 | |
| SCHEMBL19827509 | 0.91 | TSHR (0.48) | TSHRALDH1A1ANPEPERAP2EPHX1 | |
| SCHEMBL6050098 | 0.91 | TSHR (0.48) | TSHRALDH1A1ANPEPERAP2EPHX1 | |
| SCHEMBL23308200 | 0.89 | ALDH1A1 (0.44) | TSHRALDH1A1ANPEPERAP2EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9566299-B2 | Oral pharmaceutical composition of aliphatic amine polymer or salts thereof | WOCKHARDT LIMITED (IN) | 2017-02-14 | — | — | US | disclosed |
| US-20160311941-A1 | PROCESS FOR THE PREPARATION OF COLESEVELAM | CHEMI S.P.A. (IT) | 2016-10-27 | — | — | US | disclosed |
| EP-0838508-B1 | Aqueous ink composition for use in an ink-jet printer | SEIKO EPSON CORP (JP) | 2001-08-29 | — | — | EP | disclosed |
| US-5871572-A | COLORANT, WATER, A WATER-SOLUBLE ORGANIC SOLVENT, AND PECTIC ACID | SEIKO EPSON CORPORATION (JP) | 1999-02-16 | — | — | US | disclosed |
| EP-0838508-A2 | Aqueous ink composition for use in an ink-jet printer | SEIKO EPSON CORPORATION (JP) | 1998-04-29 | — | — | EP | disclosed |