SCHEMBL7775203

SCHEMBL7775203

CN(C)C(C)(Cc1ccccc1)C(=O)Cc1ccc(N2CCOCC2)cc1

nearest known ligand 0.52

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.52
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
L3MBTL1 Q9Y468 1/20 0.46
MAPT P10636 4/20 0.45
ALDH1A1 P00352 2/20 0.43
CYP1A2 P05177 1/20 0.43
CYP3A4 P08684 1/20 0.43
CYP2C19 P33261 1/20 0.43
RORC P51449 4/20 0.43
AOC3 Q16853 2/20 0.42
SLC13A5 Q86YT5 1/20 0.42
NAPEPLD Q6IQ20 2/20 0.41
ME2 P23368 1/20 0.41
ME1 P48163 1/20 0.41
ME3 Q16798 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4809212 0.85 SMN1; SMN2 (0.47) SMN1; SMN2MEN1KMT2AL3MBTL1MAPT
SCHEMBL2774235 0.85 SMN1; SMN2 (0.50) SMN1; SMN2MEN1KMT2AL3MBTL1MAPT
SCHEMBL27808128 0.84 SMN1; SMN2 (0.50) SMN1; SMN2MEN1KMT2AL3MBTL1MAPT
SCHEMBL623433 0.80 SMN1; SMN2 (0.49) SMN1; SMN2MEN1KMT2AL3MBTL1MAPT
Urea SCHEMBL27646729 0.79 SMN1; SMN2 (0.46) SMN1; SMN2MEN1KMT2AL3MBTL1MAPT
SCHEMBL18910291 0.79 GSK3B (0.44) SMN1; SMN2MEN1KMT2AL3MBTL1MAPT
SCHEMBL2307169 0.78 SMN1; SMN2 (0.56) SMN1; SMN2MEN1KMT2AMAPTALDH1A1
SCHEMBL28385736 0.77 ALDH1A1 (0.48) SMN1; SMN2MEN1KMT2AL3MBTL1MAPT
SCHEMBL16576961 0.77 NPC1 (0.50) SMN1; SMN2MEN1KMT2AL3MBTL1MAPT
SCHEMBL8898916 0.76 SMN1; SMN2 (0.51) SMN1; SMN2MEN1KMT2AL3MBTL1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1121246-A1 GLASS DECORATING METHOD USING INK COMPOSITIONS CONTAINING N-VINYL LACTAMS Revlon Consumer Products Corporation (US) 2001-08-08 EP disclosed
EP-1044238-A1 METHOD AND COMPOSITIONS FOR DECORATING VITREOUS ARTICLES WITH RADIATION CURABLE INKS HAVING IMPROVED ADHESION AND DURABILITY DECO PATENTS, INC. (US) 2000-10-18 EP disclosed
WO-2000009332-A1 GLASS DECORATING METHOD USING INK COMPOSITIONS CONTAINING N-VINYL LACTAMS REVLON CONSUMER PRODUCTS CORPORATION (US) 2000-02-24 WO disclosed
WO-1999033906-A1 METHOD AND COMPOSITIONS FOR DECORATING VITREOUS ARTICLES WITH RADIATION CURABLE INKS HAVING IMPROVED ADHESION AND DURABILITY REVLON CONSUMER PRODUCTS CORPORATION (US) 1999-07-08 WO disclosed