Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 4/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.41 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | BDKRB2 | P30411 | 3/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7775241 | 1.00 | RARB (0.41) | RARBSLC2A1GPR88ALDH1A1BDKRB2 | |
| SCHEMBL16187783 | 1.00 | RARB (0.41) | RARBSLC2A1GPR88ALDH1A1BDKRB2 | |
| SCHEMBL10631999 | 0.94 | SLC2A1 (0.45) | SLC2A1GPR88ALDH1A1MAPTNR5A1 | |
| SCHEMBL10600538 | 0.94 | SLC2A1 (0.45) | SLC2A1GPR88ALDH1A1MAPTNR5A1 | |
| SCHEMBL4354702 | 0.94 | SLC2A1 (0.45) | SLC2A1GPR88ALDH1A1MAPTNR5A1 | |
| SCHEMBL419570 | 0.94 | SLC2A1 (0.45) | SLC2A1GPR88ALDH1A1MAPTNR5A1 | |
| SCHEMBL9461059 | 0.93 | MAPT (0.48) | RARBGPR88ALDH1A1CYP2D6CYP3A4 | |
| SCHEMBL12808526 | 0.93 | PPARG (0.38) | RARBSLC2A1GPR88ALDH1A1BDKRB2 | |
| SCHEMBL7663742 | 0.92 | NR5A1 (0.51) | RARBGPR88ALDH1A1CYP3A4NR5A1 | |
| SCHEMBL12991115 | 0.92 | MGLL (0.41) | RARBSLC2A1GPR88ALDH1A1BDKRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0782995-B1 | Optically active Bis-methyldioxan derivatives and their use for electro-optical displays | ROLIC AG (CH) | 2001-08-16 | — | — | EP | disclosed |
| US-6225479-B1 | LIQUID CRYSTALLINE MIXTURES; ELECTRO-OPTICAL DEVICES | ROLIC AG (CH) | 2001-05-01 | — | — | US | disclosed |
| EP-0782995-A2 | Optically active Bis-methyldioxan derivatives and their use for electro-optical displays | Rolic AG (CH) | 1997-07-09 | — | — | EP | disclosed |