Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 7/20 | 0.52 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.43 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.43 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | DHFR | P00374 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7773300 | 1.00 | KCNH2 (0.52) | KCNH2CHRNB4CHRNA3SCN3ACYP2C19 | |
| SCHEMBL7769177 | 1.00 | KCNH2 (0.52) | KCNH2CHRNB4CHRNA3SCN3ACYP2C19 | |
| SCHEMBL7769176 | 1.00 | KCNH2 (0.52) | KCNH2CHRNB4CHRNA3SCN3ACYP2C19 | |
| SCHEMBL2038087 | 0.84 | KCNH2 (0.56) | KCNH2SCN3ACYP2C19DPP4 | |
| SCHEMBL1226045 | 0.83 | KCNH2 (0.56) | KCNH2SCN3ACYP2C19DPP4 | |
| SCHEMBL8513273 | 0.83 | KCNH2 (0.56) | KCNH2SCN3ACYP2C19DPP4 | |
| SCHEMBL5696388 | 0.83 | KCNH2 (0.56) | KCNH2SCN3ACYP2C19DPP4 | |
| SCHEMBL197425 | 0.83 | KCNH2 (0.56) | KCNH2SCN3ACYP2C19DPP4 | |
| SCHEMBL135105 | 0.83 | KCNH2 (0.56) | KCNH2SCN3ACYP2C19DPP4 | |
| SCHEMBL135106 | 0.83 | KCNH2 (0.56) | KCNH2SCN3ACYP2C19DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0723974-B1 | Derivatives of mercaptoalkanoyldipeptides, their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2001-08-16 | — | — | EP | disclosed |
| US-5741781-A | NEUTRAL ENDOPEPTIDASE AND ANGIOTENSIN CONVERTING ENZYME INHIBITORS, HYPOTENSIVE AGENTS | ADIR ET COMPAGNIE (FR) | 1998-04-21 | — | — | US | disclosed |
| EP-0723974-A1 | Derivatives of mercaptoalkanoyldipeptides, their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1996-07-31 | — | — | EP | disclosed |