SCHEMBL5696388

SCHEMBL5696388

O=C(O)[C@H]1CC[C@@H](c2ccccc2)N1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 13/20 0.56
SCN3A Q9NY46 8/20 0.56
DPP4 P27487 1/20 0.52
SCN1A P35498 1/20 0.44
SCN4A P35499 1/20 0.44
SCN7A Q01118 1/20 0.44
SCN5A Q14524 1/20 0.44
SCN9A Q15858 1/20 0.44
SCN2A Q99250 1/20 0.44
SCN8A Q9UQD0 1/20 0.44
SCN10A Q9Y5Y9 1/20 0.44
S1PR4 O95977 2/20 0.43
S1PR1 P21453 2/20 0.43
S1PR5 Q9H228 2/20 0.43
S1PR3 Q99500 1/20 0.43
CYP1A2 P05177 1/20 0.43
CYP2B6 P20813 1/20 0.43
MAOB P27338 1/20 0.43
CYP2C19 P33261 1/20 0.43
AKR1C3 P42330 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL135106 1.00 KCNH2 (0.56) KCNH2SCN3ADPP4SCN1ASCN4A
SCHEMBL8513273 1.00 KCNH2 (0.56) KCNH2SCN3ADPP4SCN1ASCN4A
SCHEMBL197791 1.00 KCNH2 (0.56) KCNH2SCN3ADPP4SCN1ASCN4A
SCHEMBL197425 1.00 KCNH2 (0.56) KCNH2SCN3ADPP4SCN1ASCN4A
SCHEMBL135105 1.00 KCNH2 (0.56) KCNH2SCN3ADPP4SCN1ASCN4A
SCHEMBL1226045 1.00 KCNH2 (0.56) KCNH2SCN3ADPP4SCN1ASCN4A
Hydrochloric Acid SCHEMBL5513962 0.98 KCNH2 (0.55) KCNH2SCN3ADPP4SCN1ASCN4A
Hydrochloric Acid SCHEMBL11235696 0.98 KCNH2 (0.55) KCNH2SCN3ADPP4SCN1ASCN4A
Hydrochloric Acid SCHEMBL8870650 0.98 KCNH2 (0.55) KCNH2SCN3ADPP4SCN1ASCN4A
Hydrochloric Acid SCHEMBL8870646 0.98 KCNH2 (0.55) KCNH2SCN3ADPP4SCN1ASCN4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 110 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240096612-A1 METHOD FOR MASS SPECTROMETRY OF ORGANIC SYNTHETIC COMPOUND SHIMADZU CORPORATION (JP) 2024-03-21 US claimed
EP-4293350-A1 METHOD FOR MASS SPECTROMETRY OF ORGANIC SYNTHETIC COMPOUND Shimadzu Corporation (JP) 2023-12-20 EP claimed
WO-2022172500-A1 METHOD FOR MASS SPECTROMETRY OF ORGANIC SYNTHETIC COMPOUND 株式会社 島津製作所 2022-08-18 WO claimed
US-20200031866-A1 PEPTIDE INHIBITORS OF SODIUM CHANNELS SPYRYX BIOSCIENCES INC (US) 2020-01-30 US claimed
WO-2019067887-A1 ENAC INHIBITOR PEPTIDES AND USES THEREOF Spyryx Biosciences, Inc. (US) 2019-04-04 WO claimed
US-20190071468-A1 PEPTIDE INHIBITORS OF SODIUM CHANNELS UNIV NORTH CAROLINA CHAPEL HILL (US) 2019-03-07 US claimed
WO-2018064499-A1 PEPTIDE INHIBITORS OF SODIUM CHANNELS Spyryx Biosciences, Inc. (US) 2018-04-05 WO claimed
US-9896481-B2 Modified mini-hepcidin peptides and methods of using thereof THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2018-02-20 US claimed
US-20170327538-A1 Peptide Inhibitors of Sodium Channels NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2017-11-16 US claimed
EP-3204029-A1 IMPROVED PEPTIDE INHIBITORS OF SODIUM CHANNELS The University of North Carolina at Chapel Hill (US) 2017-08-16 EP claimed
WO-2016057795-A1 IMPROVED PEPTIDE INHIBITORS OF SODIUM CHANNELS THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2016-04-14 WO claimed
US-20160102121-A1 Peptide Inhibitors of Sodium Channels NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2016-04-14 US claimed
US-20260108618-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF VIRAL INFECTIONS CIDARA THERAPEUTICS, INC. 2026-04-23 US disclosed
US-12569565-B2 Compositions and methods for the treatment of viral infections CIDARA THERAPEUTICS, INC. (US) 2026-03-10 US disclosed
US-20260066044-A1 SYSTEM AND METHOD FOR PREDICTION OF UNINTENDED GENE EXPRESSION IMPACT IN A FERMENTATION PROCESS ACCENTURE GLOBAL SOLUTIONS LTD (IE) 2026-03-05 US disclosed
US-20250325644-A1 ALK POLYPEPTIDES AND METHODS OF USE THEREOF ELICIO THERAPEUTICS INC (US) 2025-10-23 US disclosed
WO-2011073376-A1 PYRROLIDINE OR THIAZOLIDINE CARBOXYLIC ACID DERIVATIVES, PHARMACEUTICAL COMPOSITION AND METHODS FOR USE IN TREATING METABOLIC DISORDERSAS AS AGONISTS OF G- PROTEIN COUPLED RECEPTOR 43 (GPR43) EUROSCREEN S.A. (BE) 2011-06-23 WO disclosed
EP-1663975-A1 NOVEL GAMMA SECRETASE INHIBITORS SCHERING CORPORATION (US) 2006-06-07 EP disclosed
WO-2005028440-A1 NOVEL GAMMA SECRETASE INHIBITORS SCHERING CORPORATION (US) 2005-03-31 WO disclosed
WO-1993020099-A2 CCK AND/OR GASTRIN RECEPTOR LIGANDS FERRING B.V. (NL) 1993-10-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260108618-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF VIRAL INFECTIONS FCGR3B, FCGR1A, FCGR2A KCNH2 3399/4885SCN3A 2819/4885DPP4 156/4885
US-12569565-B2 Compositions and methods for the treatment of viral infections ALB, FCGR3B, FCGR1A KCNH2 3720/4885SCN3A 2506/4885DPP4 77/4885
US-20260066044-A1 SYSTEM AND METHOD FOR PREDICTION OF UNINTENDED GENE EXPRESSION IMPACT IN A FERMENTATION PROCESS SCLY, SPOUT1, ADH5 KCNH2 4492/4885SCN3A 3455/4885DPP4 2237/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.