Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.30 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.30 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.30 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.30 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7770639 | 0.84 | MAOB (0.38) | — | |
| SCHEMBL7778151 | 0.83 | PPARA (0.32) | BACE1 | |
| SCHEMBL7777946 | 0.82 | FFAR1 (0.35) | BACE1 | |
| SCHEMBL6156231 | 0.81 | MAOB (0.41) | BACE1 | |
| SCHEMBL6885983 | 0.80 | CYP3A4 (0.46) | BACE1GABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL7614800 | 0.80 | BACE1 (0.32) | BACE1 | |
| SCHEMBL3278871 | 0.79 | VDR (0.46) | BACE1 | |
| SCHEMBL3278878 | 0.79 | VDR (0.46) | BACE1 | |
| SCHEMBL3278876 | 0.79 | VDR (0.46) | BACE1 | |
| SCHEMBL17336265 | 0.79 | BACE1 (0.36) | BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1124779-A1 | VITAMIN D ANALOGUES | Galderma Research & Development, S.N.C. (FR) | 2001-08-22 | — | — | EP | disclosed |
| WO-2000026167-A1 | VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2000-05-11 | — | — | WO | disclosed |