Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 4/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 3/20 | 0.30 |
| ▸ | CA1 | P00915 | 3/20 | 0.30 |
| ▸ | CA2 | P00918 | 3/20 | 0.30 |
| ▸ | CA7 | P43166 | 3/20 | 0.30 |
| ▸ | CA9 | Q16790 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3718636 | 0.83 | TSHR (0.30) | TSHR | |
| SCHEMBL11566231 | 0.81 | DPP4 (0.33) | — | |
| SCHEMBL11442409 | 0.80 | TSHR (0.42) | TSHRALDH1A1MAPTKDM4EHIF1A | |
| SCHEMBL27810375 | 0.80 | TSHR (0.42) | TSHRALDH1A1MAPTKDM4EHIF1A | |
| SCHEMBL7645726 | 0.77 | — | — | |
| SCHEMBL7436520 | 0.76 | TSHR (0.39) | TSHRALDH1A1MAPTKDM4EHIF1A | |
| SCHEMBL9347901 | 0.75 | — | — | |
| SCHEMBL18643740 | 0.75 | — | — | |
| SCHEMBL28446509 | 0.75 | — | — | |
| SCHEMBL2911451 | 0.75 | TSHR (0.42) | TSHRHCAR2LMNACA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114763319-B | Method for co-producing valproamide and sodium valproate | 湖南大学 | 2023-03-31 | — | — | CN | disclosed |
| US-20170028099-A1 | METHOD FOR THE PRODUCTION OF POLY(2-OCTYL CYANOACRYLATE)-POLYISOBUTYLENE CO-NETWORK, AND SUPER INITIATORS THEREFOR | THE UNIVERSITY OF AKRON (US) | 2017-02-02 | — | — | US | disclosed |
| WO-2015018797-A2 | ANTIVIRAL COMPOUNDS | HAPLOGEN GMBH (AT) | 2015-02-12 | — | — | WO | disclosed |
| EP-0839818-B1 | Optically active diphosphines, transition metal complex containing the same, and process for producing an optically active compound using the complex | TAKASAGO PERFUMERY CO LTD (JP) | 2001-08-16 | — | — | EP | disclosed |
| US-5789609-A | CATALYST FOR ASSYMETRIC SYNTHESIS, REACTION OF AN A-CYANO ESTER AND A VINYL KETONE TO PRODUCE AN OXO CYANO ESTER | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1998-08-04 | — | — | US | disclosed |
| EP-0839818-A1 | Optically active diphosphine, transition metal complex containing the same, and process for producing optically active compound using the complex | Takasago International Corporation (JP) | 1998-05-06 | — | — | EP | disclosed |
| US-RE30420-E | DIURETIC, HYPOTENSIVE | BAYER AKTIENGESELLSCHAFT (DE) | 1980-10-21 | — | — | US | disclosed |
| US-4112227-A | DIURETIC, SALURETIC, ANTIHYPERTENSIVE, ANTITHROMBOTIC | BAYER AKTIENGESELLSCHAFT (DE) | 1978-09-05 | — | — | US | disclosed |
| US-4081596-A | DIURETIC, SALURETIC, ANTIHYPERTENSIVE, ANTITHROMBOTIC | BAYER AKTIENGESELLSCHAFT (DT) | 1978-03-28 | — | — | US | disclosed |
| US-4056533-A | HYPOTENSIVE AGENTS, ANTICOAGULANTS, DIURETICS | BAYER AKTIENGESELLSCHAFT (DT) | 1977-11-01 | — | — | US | disclosed |
| US-4005215-A | DIURETIC | BAYER AKTIENGESELLSCHAFT (DT) | 1977-01-25 | — | — | US | disclosed |
| US-4000294-A | DIURESIS OR SALURESIS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-12-28 | — | — | US | disclosed |
| US-3992404-A | DIURETICS, SALURETICS, ANTIHYPERTENSIVE AGENTS, AND ANTITHROMBOTIC AGENTS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-11-16 | — | — | US | disclosed |
| US-3978077-A | DIURETIC, HYPOTENSIVE, ANTITHROMBOTIC | BAYER AKTIENGESELLSCHAFT (GB) | 1976-08-31 | — | — | US | disclosed |
| US-3957814-A | DIURETICS, SALURETICS, HYPOTENSIVE AGENTS, ANTITHROMBOTIC | BAYER AKTIENGESELLSCHAFT (DT) | 1976-05-18 | — | — | US | disclosed |
| US-3952008-A | DIURETIC, SALURETIC, HYPOTENSIVE, ANTITHROMBOTIC | BAYER AKTIENGESELLSCHAFT (DT) | 1976-04-20 | — | — | US | disclosed |