Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 3/20 | 0.32 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.32 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | GNPAT | O15228 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8350972 | 0.86 | ECE1 (0.36) | TSHRALDH1A1SMN1; SMN2MAPTKMT2A | |
| SCHEMBL176159 | 0.84 | CA2 (0.39) | TSHRALDH1A1SMN1; SMN2MAPTGNPAT | |
| SCHEMBL176161 | 0.84 | CA2 (0.39) | TSHRALDH1A1SMN1; SMN2MAPTGNPAT | |
| SCHEMBL8994505 | 0.82 | CA2 (0.38) | ALDH1A1SMN1; SMN2GNPAT | |
| SCHEMBL5141196 | 0.81 | TSHR (0.44) | TSHRMAPTSLC6A2SLC6A4BLM | |
| SCHEMBL27942121 | 0.81 | TSHR (0.44) | TSHRMAPTSLC6A2SLC6A4BLM | |
| SCHEMBL4970112 | 0.78 | TSHR (0.34) | TSHRALDH1A1SMN1; SMN2MAPTKMT2A | |
| SCHEMBL3043575 | 0.78 | TSHR (0.34) | TSHRALDH1A1SMN1; SMN2MAPTKMT2A | |
| SCHEMBL7482390 | 0.77 | ECE1 (0.39) | TSHRALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL10972602 | 0.77 | ECE1 (0.39) | TSHRALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0784050-B1 | Novel aspartylamide derivatives and sweeteners | AJINOMOTO KK (JP) | 2001-10-04 | — | — | EP | disclosed |
| US-6010733-A | ARTIFICIAL SWEETENER | AJINOMOTO CO., INC. (JP) | 2000-01-04 | — | — | US | disclosed |
| US-5861356-A | SUPPLYING FERTILIZER WHEN HYDROLYZED WITH WATER | DONLAR CORPORATION (US) | 1999-01-19 | — | — | US | disclosed |
| WO-1998030100-A1 | METHOD AND COMPOSITION FOR ENHANCED PLANT PRODUCTIVITY | DONLAR CORPORATION (US) | 1998-07-16 | — | — | WO | disclosed |
| EP-0784050-A1 | Novel aspartylamide derivatives and sweeteners | Ajinomoto Co., Inc. (JP) | 1997-07-16 | — | — | EP | disclosed |