SCHEMBL7775556

SCHEMBL7775556

CCOC(Cc1ccc(OCCN(C)C2C3=CC=CCC3=CCc3ccccc32)cc1)C(=O)O

nearest known ligand 0.73

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PPARG P37231 18/20 0.73
PPARA Q07869 15/20 0.51
PPARD Q03181 4/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6716082 0.85 PPARG (1.00) PPARGPPARAPPARD
SCHEMBL7775554 0.82 PPARG (0.52) PPARGPPARAPPARD
SCHEMBL6717251 0.80 PPARG (0.88) PPARGPPARAPPARD
SCHEMBL6717990 0.80 PPARG (0.88) PPARGPPARAPPARD
SCHEMBL6718076 0.79 PPARG (0.87) PPARGPPARAPPARD
SCHEMBL6719210 0.79 PPARG (0.87) PPARGPPARAPPARD
SCHEMBL6717495 0.78 PPARG (0.85) PPARGPPARAPPARD
SCHEMBL6717459 0.78 PPARG (0.85) PPARGPPARAPPARD
SCHEMBL6719858 0.78 PPARG (0.85) PPARGPPARAPPARD
SCHEMBL6714549 0.78 PPARG (0.85) PPARGPPARAPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1123269-A1 NEW COMPOUNDS, THEIR PREPARATION AND USE NOVO NORDISK A/S (DK) 2001-08-16 EP claimed
WO-2000023417-A1 NEW COMPOUNDS, THEIR PREPARATION AND USE NOVO NORDISK A/S (DK) 2000-04-27 WO claimed