SCHEMBL7775554

SCHEMBL7775554

CCOC(Cc1ccc(OCCNCC2C3=CC=CCC3=CCc3ccccc32)cc1)C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PPARG P37231 18/20 0.52
PPARA Q07869 15/20 0.51
PPARD Q03181 4/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6716080 0.85 PPARG (0.67) PPARGPPARAPPARD
SCHEMBL7775556 0.82 PPARG (0.73) PPARGPPARAPPARD
SCHEMBL7800578 0.77 PPARA (0.62) PPARGPPARAPPARD
SCHEMBL7788160 0.76 PPARG (0.56) PPARGPPARAPPARD
SCHEMBL7596966 0.75 PPARG (0.69) PPARGPPARAPPARD
SCHEMBL7775818 0.72 PPARG (0.69) PPARGPPARAPPARD
SCHEMBL7775819 0.72 PPARG (0.69) PPARGPPARAPPARD
SCHEMBL6715846 0.71 PPARG (0.71) PPARGPPARAPPARD
SCHEMBL7696494 0.70 LTA4H (0.49) PPARGPPARAPPARD
SCHEMBL6731204 0.69 PPARA (0.90) PPARGPPARAPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1123269-A1 NEW COMPOUNDS, THEIR PREPARATION AND USE NOVO NORDISK A/S (DK) 2001-08-16 EP claimed
WO-2000023417-A1 NEW COMPOUNDS, THEIR PREPARATION AND USE NOVO NORDISK A/S (DK) 2000-04-27 WO claimed