⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19957506 | 0.78 | — | — | |
| SCHEMBL13558734 | 0.73 | — | — | |
| SCHEMBL7962241 | 0.73 | — | — | |
| SCHEMBL7232483 | 0.69 | CHRNB2 (0.33) | — | |
| SCHEMBL8028062 | 0.65 | — | — | |
| SCHEMBL6538704 | 0.65 | PTGER2 (0.34) | — | |
| SCHEMBL7775680 | 0.64 | MAPT (0.32) | — | |
| SCHEMBL11045149 | 0.63 | — | — | |
| SCHEMBL1659670 | 0.63 | — | — | |
| SCHEMBL13448633 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0638077-B1 | CHIRAL CYCLOPENTENE DERIVATIVES AND THEIR PREPARATION | CHIROTECH TECHNOLOGY LTD (GB) | 2001-09-19 | — | — | EP | claimed |
| EP-0638077-A1 | CHIRAL CYCLOPENTENE DERIVATIVES AND THEIR PREPARATION | Chiroscience Limited (GB) | 1995-02-15 | — | — | EP | claimed |
| WO-1993021175-A1 | CHIRAL CYCLOPENTENE DERIVATIVES AND THEIR PREPARATION | CHIROSCIENCE LIMITED (GB) | 1993-10-28 | — | — | WO | claimed |
| EP-0638077-B1 | CHIRAL CYCLOPENTENE DERIVATIVES AND THEIR PREPARATION | CHIROTECH TECHNOLOGY LTD (GB) | 2001-09-19 | — | — | EP | disclosed |
| EP-0638077-B1 | CHIRAL CYCLOPENTENE DERIVATIVES AND THEIR PREPARATION | CHIROTECH TECHNOLOGY LTD (GB) | 2001-09-19 | — | — | EP | disclosed |
| US-5840923-A | Chiral cyclopentene derivatives and their preparation | CHIROSCIENCE LIMITED (GB) | 1998-11-24 | — | — | US | disclosed |
| US-5840923-A | Chiral cyclopentene derivatives and their preparation | CHIROSCIENCE LIMITED (GB) | 1998-11-24 | — | — | US | disclosed |
| EP-0638077-A1 | CHIRAL CYCLOPENTENE DERIVATIVES AND THEIR PREPARATION | Chiroscience Limited (GB) | 1995-02-15 | — | — | EP | disclosed |
| EP-0638077-A1 | CHIRAL CYCLOPENTENE DERIVATIVES AND THEIR PREPARATION | Chiroscience Limited (GB) | 1995-02-15 | — | — | EP | disclosed |
| WO-1994007888-A1 | CHIRAL COMPOUNDS AND THEIR USE | CHIROSCIENCE LIMITED (GB) | 1994-04-14 | — | — | WO | disclosed |
| WO-1993021175-A1 | CHIRAL CYCLOPENTENE DERIVATIVES AND THEIR PREPARATION | CHIROSCIENCE LIMITED (GB) | 1993-10-28 | — | — | WO | disclosed |
| WO-1993021175-A1 | CHIRAL CYCLOPENTENE DERIVATIVES AND THEIR PREPARATION | CHIROSCIENCE LIMITED (GB) | 1993-10-28 | — | — | WO | disclosed |