Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | P2RX4 | Q99571 | 13/20 | 0.61 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.53 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.53 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.53 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.50 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | SCN4A | P35499 | 1/20 | 0.49 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.49 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.49 |
| ▸ | P2RX1 | P51575 | 4/20 | 0.48 |
| ▸ | P2RX3 | P56373 | 4/20 | 0.48 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.48 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15920342 | 0.79 | P2RX4 (0.67) | P2RX4GRIN1GRIN2AGRIN2BMTNR1A | |
| SCHEMBL11721111 | 0.75 | P2RX4 (0.71) | P2RX4GRIN1GRIN2AGRIN2BMTNR1A | |
| SCHEMBL11727362 | 0.75 | P2RX4 (0.74) | P2RX4GRIN1GRIN2AGRIN2BMTNR1A | |
| SCHEMBL15603438 | 0.74 | P2RX4 (0.66) | P2RX4GRIN1GRIN2AGRIN2BMTNR1A | |
| SCHEMBL11113845 | 0.73 | P2RX4 (0.67) | P2RX4GRIN1GRIN2AGRIN2BMTNR1A | |
| SCHEMBL11577183 | 0.73 | P2RX4 (0.49) | KMT2AP2RX4GRIN1GRIN2AGRIN2B | |
| SCHEMBL11039708 | 0.73 | GRIN1 (0.92) | P2RX4GRIN1GRIN2AGRIN2BLMNA | |
| SCHEMBL11770681 | 0.73 | P2RX4 (0.71) | P2RX4GRIN1GRIN2AGRIN2BMTNR1A | |
| SCHEMBL13051502 | 0.73 | BCHE (0.68) | P2RX4GRIN1GRIN2AGRIN2BMTNR1A | |
| Hydrochloric Acid SCHEMBL11574541 | 0.72 | P2RX4 (0.48) | KMT2AP2RX4GRIN1GRIN2AGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0277095-B2 | Method for preparing N,N-(dibenzohexatrienylene) ureas | NOVARTIS AG (CH) | 2001-09-05 | — | — | EP | disclosed |
| EP-0277095-B1 | METHOD FOR PREPARING N,N-(DIBENZOHEXATRIENYLENE) UREAS | Novartis AG (CH) | 1992-04-01 | — | — | EP | disclosed |