Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX4 | Q99571 | 14/20 | 0.67 |
| ▸ | BCHE | P06276 | 1/20 | 0.61 |
| ▸ | ACHE | P22303 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | SCN4A | P35499 | 1/20 | 0.58 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.58 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.58 |
| ▸ | P2RX1 | P51575 | 5/20 | 0.56 |
| ▸ | P2RX3 | P56373 | 5/20 | 0.56 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.56 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.54 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.54 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.50 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.50 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15603438 | 0.82 | P2RX4 (0.66) | P2RX4LMNATSHRMAPK1SCN4A | |
| SCHEMBL15920342 | 0.80 | P2RX4 (0.67) | P2RX4BCHELMNATSHRMAPK1 | |
| SCHEMBL14714325 | 0.79 | P2RX4 (0.67) | P2RX4LMNATSHRMAPK1SCN4A | |
| SCHEMBL11114101 | 0.79 | BCHE (0.50) | P2RX4BCHEACHELMNATSHR | |
| SCHEMBL7980250 | 0.78 | P2RX4 (0.67) | P2RX4LMNATSHRMAPK1SCN4A | |
| SCHEMBL11112161 | 0.77 | BCHE (0.49) | P2RX4BCHEACHELMNATSHR | |
| SCHEMBL9555484 | 0.77 | P2RX4 (1.00) | P2RX4BCHELMNATSHRMAPK1 | |
| SCHEMBL220291 | 0.77 | P2RX4 (0.58) | P2RX4LMNATSHRMAPK1SCN4A | |
| SCHEMBL21473321 | 0.75 | P2RX4 (0.57) | P2RX4LMNATSHRMAPK1SCN4A | |
| SCHEMBL11118498 | 0.75 | BCHE (0.47) | P2RX4BCHEACHELMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0108715-A1 | Dibenzazepine carboxamides | CIBA-GEIGY AG (CH) | 1984-05-16 | — | — | EP | claimed |
| WO-2014097137-A2 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF SEIZURES AND NEUROLOGIC DISEASES | KANDULA MAHESH (IN) | 2014-06-26 | — | — | WO | disclosed |
| EP-0108715-A1 | Dibenzazepine carboxamides | CIBA-GEIGY AG (CH) | 1984-05-16 | — | — | EP | disclosed |