SCHEMBL7775808

SCHEMBL7775808

CCCCCCCCCCc1nc2c(Br)sc(Br)c2nc1CCCCCCCCCC

nearest known ligand 0.38

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.38
KCNH2 Q12809 1/20 0.37
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
PKM P14618 1/20 0.34
HPGD P15428 1/20 0.34
DHFR P00374 1/20 0.33
GPR35 Q9HC97 4/20 0.33
GPR84 Q9NQS5 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28062511 1.00 ALDH1A1 (0.38) ALDH1A1KCNH2MEN1KMT2APKM
SCHEMBL14876721 1.00 ALDH1A1 (0.38) ALDH1A1KCNH2MEN1KMT2APKM
SCHEMBL28062512 1.00 ALDH1A1 (0.38) ALDH1A1KCNH2MEN1KMT2APKM
SCHEMBL7776237 0.98 MEN1 (0.36) ALDH1A1KCNH2MEN1KMT2APKM
SCHEMBL14876707 0.91 ATM (0.38) ALDH1A1KCNH2PKMHPGDGPR35
SCHEMBL19625907 0.81 KCNH2 (0.46) ALDH1A1KCNH2MEN1KMT2APKM
SCHEMBL3822615 0.78 ALDH1A1 (0.39) ALDH1A1KCNH2MEN1KMT2APKM
SCHEMBL621757 0.77 KCNH2 (0.46) ALDH1A1KCNH2DHFRGPR84
SCHEMBL15967965 0.77 KCNH2 (0.46) ALDH1A1KCNH2DHFRGPR84
SCHEMBL14762926 0.77 KCNH2 (0.46) ALDH1A1KCNH2DHFRGPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0885251-B1 SUBSTITUTED POLYTHIOPHENES, PROCESSES FOR THEIR PREPARATION AND THEIR USE BASF AG (DE) 2001-08-16 EP disclosed
US-6242561-B1 USED AS SEMICONDUCTORS; ELECTROCHROMIC AND ANTISTATIC PROPERTIES BASF AKTIENGESELLSCHAFT (DE) 2001-06-05 US disclosed