Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 11/20 | 0.72 |
| ▸ | TBXA2R | P21731 | 8/20 | 0.72 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7460400 | 0.95 | TBXAS1 (0.70) | TBXAS1TBXA2RHDAC8 | |
| SCHEMBL7467932 | 0.94 | TBXAS1 (0.73) | TBXAS1TBXA2RHDAC8 | |
| SCHEMBL7463923 | 0.91 | TBXAS1 (0.72) | TBXAS1TBXA2RHDAC8 | |
| SCHEMBL7459983 | 0.90 | TBXAS1 (0.63) | TBXAS1TBXA2RHDAC8 | |
| SCHEMBL7459288 | 0.90 | TBXAS1 (0.69) | TBXAS1TBXA2RHDAC8 | |
| SCHEMBL8114551 | 0.90 | TBXAS1 (0.60) | TBXAS1TBXA2RHDAC8 | |
| SCHEMBL7220602 | 0.89 | TBXAS1 (0.68) | TBXAS1TBXA2RHDAC8 | |
| SCHEMBL7778082 | 0.88 | TBXAS1 (0.69) | TBXAS1TBXA2RHDAC8 | |
| SCHEMBL7771863 | 0.87 | TBXAS1 (0.65) | TBXAS1TBXA2RHDAC8 | |
| SCHEMBL9015441 | 0.87 | TBXA2R (0.74) | TBXAS1TBXA2RHDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0864561-B1 | Benzenesulfonylamine derivatives,process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2001-09-05 | — | — | EP | disclosed |
| EP-0864561-A1 | Benzenesulfonylamine derivatives,process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1998-09-16 | — | — | EP | disclosed |